JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB120366

(±)-BAYK8644, L-type Ca2+ channel activator

Be the first to review this product! Submit a review

|

(0 Publication)

MW 356.3 Da, Purity >99%. Potent L-type Ca2+ channel activator (EC50 = 17.3 nM). Centrally active following systemic administration.

View Alternative Names

ANKTM 1, Ankyrin-like with transmembrane domains protein 1, CAC1C_HUMAN, CAC1D_HUMAN, CAC1S_HUMAN, CACH 2, CACH1, CACH3, CACN 2, CACN1, CACN4, CACNA 1D, CACNL1A1, CACNL1A2, CACNL1A3, CCHL1A1, CCHL1A2, CCHL1A3, CGEF 2, CaV1.2, Cach1b, Calcium channel, Calcium channel L type alpha 1 polypeptide isoform 1 cardiac muscle, Calcium channel L type alpha 1 polypeptide isoform 2, Calcium channel cardic dihydropyridine sensitive alpha 1 subunit, Calcium channel neuroendocrine/brain type alpha 1 subunit, Calcium channel voltage dependent L type alpha 1, Calcium channel voltage dependent L type alpha 1C subunit, Calcium channel voltage dependent L type alpha 1D subunit, Calcium channel, L type, alpha 1 polypeptide, isoform 3, skeletal, Calcium channel, L type, alpha 1 polypeptide, isoform 3, skeletal muscle, Calcium channel, L type, alpha 1 polypeptide, isoform 3, skeletal muscle, hypokalemic periodic paralysis, Calcium channel, skeletal muscle dihydropyridine sensitive , alpha 1 subunit, Calcium channel, voltage dependent, L type, alpha 1S subunit, Calcium channel, voltage-dependent, L type, alpha 1S subunit, b, Cav1.1, Cav1.3, DHPR alpha 1, DHPR alpha 1 subunit, Dihydropyridine receptor, Dihydropyridine sensitive L type calcium channel alpha 1 subunit, Epac 2, Exchange factor directly activated by cAMP 2, Exchange protein directly activated by cAMP 2, HOKPP, HypoPP, L type, LQT8, MHS5, Malignant hyperthermia susceptibility 5, Nbla00496, PASNA, Putative protein product of Nbla00496, RAPGEF 4, ROB1, RPGF4_HUMAN, Rap guanine nucleotide exchange factor (GEF) 4, Rap guanine nucleotide exchange factor 4, SANDD, TRPA1_HUMAN, TS, TTPP1, Transformation-sensitive protein p120, Transient receptor potential cation channel subfamily A member 1, Voltage dependent L type calcium channel alpha 1C subunit, Voltage gated L type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*, Voltage gated calcium channel alpha 1 subunit, Voltage gated calcium channel alpha subunit Cav1.2, Voltage gated calcium channel alpha subunit Cav1.3, Voltage-dependent L-type calcium channel subunit alpha-1C, Voltage-dependent L-type calcium channel subunit alpha-1D, Voltage-dependent L-type calcium channel subunit alpha-1S, Voltage-gated calcium channel subunit alpha Cav1.1, Voltage-gated calcium channel subunit alpha Cav1.2, Voltage-gated calcium channel subunit alpha Cav1.3, alpha-1 polypeptide, cAMP-GEFII, cAMP-regulated guanine nucleotide exchange factor II, cardiac muscle, fmd, isoform 1, isoform 2, isoform 3, sj

1 Images
Chemical Structure - (±)-BAYK8644, L-type Ca2+ channel activator (AB120366)
  • Chemical Structure

Lab

Chemical Structure - (±)-BAYK8644, L-type Ca2+ channel activator (AB120366)

2D chemical structure image of ab120366, BAYK8644, L-type Ca2+ channel activator

Key facts

CAS number

71145-03-4

Purity

>99%

Form

Solid

form

Molecular weight

356.3 Da

Molecular formula

C<sub>1</sub><sub>6</sub>H<sub>1</sub><sub>5</sub>F<sub>3</sub>N<sub>2</sub>O<sub>4</sub>

PubChem

2303

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 100 mM

Biochemical name

Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate

Biological description

Potent L-type Ca2+ channel activator (EC50 = 17.3 nM). Centrally active following systemic administration.

Canonical smiles

CC1=C(C(C(=C(N1)C)[N+](=O)[O-])C2=CC=CC=C2C(F)(F)F)C(=O)OC

InChi

InChI=1S/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3

InChiKey

ZFLWDHHVRRZMEI-UHFFFAOYSA-N

IUPAC Name

methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com