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MW 304.43 g/mol. Potent, selective inhibitor phosphodiesterase PDE-11 inhibitor (IC50 = 0.28 μM). IC50s for PDE1-10 are greater than 100 μM. Significantly elevates cAMP levels and cortisol production in H295R human adenocarcinoma cells.

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Images

Chemical Structure - BC-11-38, PDE-11 inhibitor (AB146156), expandable thumbnail

Key facts

CAS number
686770-80-9
Molecular weight
304.43 g/mol
Molecular formula
C15H16N2OS2
Nature
Synthetic

Target data

Recommended products

MW 304.43 g/mol. Potent, selective inhibitor phosphodiesterase PDE-11 inhibitor (IC50 = 0.28 μM). IC50s for PDE1-10 are greater than 100 μM. Significantly elevates cAMP levels and cortisol production in H295R human adenocarcinoma cells.

Key facts

Biological description

Potent, selective inhibitor phosphodiesterase PDE-11 inhibitor (IC50 = 0.28 μM). IC50s for PDE1-10 are greater than 100 μM. Significantly elevates cAMP levels and cortisol production in H295R human adenocarcinoma cells.

Canonical SMILES
O=C1C=3SCCC=3N=C(SCCC)N1C2CCCCC2
InChI
InChI=1S/C15H16N2OS2/c1-2-9-20-15-16-12-8-10-19-13(12)14(18)17(15)11-6-4-3-5-7-11/h3-7H,2,8-10H2,1H3
InChIKey
YHNDCCKFNWDQGW-UHFFFAOYSA-N

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months

Product promise

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1 product image

  • Chemical Structure - BC-11-38, PDE-11 inhibitor (ab146156), expandable thumbnail

    Chemical Structure - BC-11-38, PDE-11 inhibitor (ab146156)

    2D chemical structure image of ab146156, BC-11-38, PDE-11 inhibitor

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Product protocols

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