Products
Sample Prep & Detection Kits
Conjugation kitsPurification kitsSample preparation kitsChromogen kitsIHC kitsChIP kitsAccessory Reagents & Controls
Accessory reagents & controlsBiochemicals
BiochemicalsProteins and Peptides
Proteins and peptidesOur latest ELISA kit: Human Tau (phospho T217) - Intracellular
Highly sensitive kit offering the most promising biomarkers for Alzheimer’s disease diagnostics. Learn about all product ranges with our product overviews.
Resources
Featured events
Make new connections at our global events.
Support
Our programs
New Lab Program
Get a head start with our exclusive new lab discount. Enjoy 20% off and free shipping for three months.
New Biotech Program
Just starting out? Get 15% off and free shipping to your lab for six months.
Product promise
Peace of mind that all products perform as stated.
Product reviews
Leave reviews, get rewarded and help your community.
Trial program
Try untested species and applications to earn money off your next order.
MW 372.9 Da, Purity >98%. Potent inhibitor of TRPV1 (IC50 values are 35 and 6 nM for capsaicin and acid-induced activation respectively). Inhibits TRPM8 (IC50 = 0.8 μM). Reduces hyperalgesia in vivo..
Alternative names=Capsaicin receptor, DKFZp434K0220, Eag-related protein 1, Ether a go go related potassium channel protein, Ether-a-go-go-related gene potassium channel 1, Ether-a-go-go-related protein 1, H-ERG, KCNH2_HUMAN, Kv11.1, LQT 2, LTrpC-6, Long transient receptor potential channel 6, MGC2849, OTRPC1, Osm-9-like TRP channel 1, Potassium channel HERG, Potassium voltage gated channel subfamily H (eag related) member 2, Potassium voltage-gated channel subfamily H member 2, SQT1, Short form of the TRPM8 cationic channel, TRPM8_HUMAN, TRPV1_HUMAN, Transient receptor potential cation channel subfamily M member 8, Transient receptor potential cation channel subfamily V member 1, Trp-p8, VR 1, Vanilloid receptor 1, Vanilloid receptor subtype 1, Voltage gated potassium channel, subfamily H, member 2, Voltage-gated potassium channel subunit Kv11.1, eag homolog, hERG-1, transient receptor potential-p8
- CAS number
393514-24-4
- Purity
> 98%
- Form
Solid
- Molecular weight
372.9 Da
- Molecular formula
C20H25ClN4O
- PubChem identifier
9929425
- Nature
Synthetic
Images
Recommended products
MW 372.9 Da, Purity >98%. Potent inhibitor of TRPV1 (IC50 values are 35 and 6 nM for capsaicin and acid-induced activation respectively). Inhibits TRPM8 (IC50 = 0.8 μM). Reduces hyperalgesia in vivo..
Alternative names=Capsaicin receptor, DKFZp434K0220, Eag-related protein 1, Ether a go go related potassium channel protein, Ether-a-go-go-related gene potassium channel 1, Ether-a-go-go-related protein 1, H-ERG, KCNH2_HUMAN, Kv11.1, LQT 2, LTrpC-6, Long transient receptor potential channel 6, MGC2849, OTRPC1, Osm-9-like TRP channel 1, Potassium channel HERG, Potassium voltage gated channel subfamily H (eag related) member 2, Potassium voltage-gated channel subfamily H member 2, SQT1, Short form of the TRPM8 cationic channel, TRPM8_HUMAN, TRPV1_HUMAN, Transient receptor potential cation channel subfamily M member 8, Transient receptor potential cation channel subfamily V member 1, Trp-p8, VR 1, Vanilloid receptor 1, Vanilloid receptor subtype 1, Voltage gated potassium channel, subfamily H, member 2, Voltage-gated potassium channel subunit Kv11.1, eag homolog, hERG-1, transient receptor potential-p8
Key facts
- CAS number
393514-24-4
- Purity
> 98%
- Form
Solid
- Molecular weight
372.9 Da
- Molecular formula
C20H25ClN4O
- PubChem identifier
9929425
- Nature
Synthetic
- Biochemical name
Bctc
- Biological description
Potent inhibitor of TRPV1 (IC50 values are 35 and 6 nM for capsaicin and acid-induced activation respectively). Inhibits TRPM8 (IC50 = 0.8 μM). Reduces hyperalgesia in vivo.
- Canonical SMILES
CC(C)(C)C1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=C(C=CC=N3)Cl
- InChI
InChI=1S/C20H25ClN4O/c1-20(2,3)15-6-8-16(9-7-15)23-19(26)25-13-11-24(12-14-25)18-17(21)5-4-10-22-18/h4-10H,11-14H2,1-3H3,(H,23,26)
- InChIKey
ROGUAPYLUCHQGK-UHFFFAOYSA-N
- IUPAC name
N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)piperazine-1-carboxamide
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
Ambient
- Storage information
The product can be stored for up to 12 months
Product promise
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com