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AB145620

BEC, Arginase inhibitor

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MW 193.03 Da, Purity >98%. Potent, slow binding, competitive arginase inhibitor (Ki values are 30 and 500 nM for human arginase II and rat arginase I respectively). Enhances NO-dependent smooth muscle relaxation. Shows pro-inflammatory effects in vivo. Orally active.
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Chemical Structure - BEC, Arginase inhibitor (AB145620)
  • Chemical Structure

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Chemical Structure - BEC, Arginase inhibitor (AB145620)

2D chemical structure image of ab145620, BEC, Arginase inhibitor

Key facts

CAS number

63107-40-4

Purity

>98%

Form

Solid

form

Molecular weight

193.03 Da

Molecular formula

C<sub>5</sub>H<sub>1</sub><sub>2</sub>BNO<sub>4</sub>S

PubChem

9877608

Nature

Synthetic

Solubility

Soluble in PBS (pH 7.2) to 25 mM

Biochemical name

S-(2-boronoethyl)-L-cysteine

Biological description

Potent, slow binding, competitive arginase inhibitor (Ki values are 30 and 500 nM for human arginase II and rat arginase I respectively). Enhances NO-dependent smooth muscle relaxation. Shows pro-inflammatory effects in vivo. Orally active.

Canonical smiles

B(CCSCC(C(=O)O)N)(O)O

Isomeric smiles

B(CCSC[C@@H](C(=O)O)N)(O)O

InChi

InChI=1S/C5H12BNO4S/c7-4(5(8)9)3-12-2-1-6(10)11/h4,10-11H,1-3,7H2,(H,8,9)/t4-/m0/s1

InChiKey

OTJHLDXXJHAZTN-BYPYZUCNSA-N

IUPAC Name

(2R)-2-amino-3-(2-boronoethylsulfanyl)propanoic acid

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 2359 BEC. 2359-5 is the same size as the 5 mg size of ab145620.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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