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AB145909

Bestatin methyl ester, neutral aminopeptidase inhibitor

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MW 322.4 g/mol, Purity >97%. Cell-permeable derivative of Bestatin (ab141417). Displays slightly stronger inhibition of neutral aminopeptidase than Bestatin but has much weaker activity against basic aminopeptidase. Augments Fas- or TNF-α-induced apoptosis in solid tumor cell lines.
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Chemical Structure - Bestatin methyl ester, neutral aminopeptidase inhibitor (AB145909)
  • Chemical Structure

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Chemical Structure - Bestatin methyl ester, neutral aminopeptidase inhibitor (AB145909)

2D chemical structure image of ab145909, Bestatin methyl ester, neutral aminopeptidase inhibitor

Key facts

CAS number

65322-89-6

Purity

>97%

Molecular weight

322.4 g/mol

Molecular formula

C<sub>1</sub><sub>7</sub>H<sub>2</sub><sub>6</sub>N<sub>2</sub>O<sub>4</sub>

Nature

Synthetic

Solubility

Soluble in DMSO

Biological description

Cell-permeable derivative of Bestatin (ab141417). Displays slightly stronger inhibition of neutral aminopeptidase than Bestatin but has much weaker activity against basic aminopeptidase. Augments Fas- or TNF-α-induced apoptosis in solid tumor cell lines.

IUPAC Name

(-)-N-[(2S, 3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine methyl ester

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Complementary Products

Biochemicals

AB142405

Bestatin hydrochloride, aminopeptidase inhibitor

Chemical Structure - Bestatin hydrochloride, aminopeptidase inhibitor (AB142405)

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Proteins & Peptides

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Primary Antibodies

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Primary Antibodies

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Anti-CD13 antibody [EPR4058]

RabMAb|Recombinant|KO Validated|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD13 antibody [EPR4058] (AB108310)

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months
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Product protocols

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