Beta-amyloid peptide (1-42) (human) is with purity of > 95%.
- Reconstitute with PBS at 1 mg/mL
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37 Publications for All applications
- Frontiers in aging neuroscience 15:12757932023Development of a diagnostic and risk prediction model for Alzheimer's disease through integration of single-cell and bulk transcriptomic analysis of glutamine metabolism.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYan Guo,Tingru Zhao,Xi Chu,Zhenyun ChengPubMed 38020758
- Aging 15:12209-122242023Effects of amyloid β (Aβ)42 and Gasdermin D on the progression of Alzheimer's disease and through the regulation of astrocyte pyroptosis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesWenjuan Hong,Chengping Hu,Can Wang,Binggen Zhu,Ming Tian,Hongyun QinPubMed 37921870
- International journal of molecular sciences 24:2023Plasmalogen Improves Memory Function by Regulating Neurogenesis in a Mouse Model of Alzheimer's Diseases.Applications:Unspecified applicationReactive species:Unspecified reactive speciesRongzi Li,Wei Xiong,Boying Li,Yixuan Li,Bing Fang,Xifan Wang,Fazheng RenPubMed 37569610
- Brain : a journal of neurology 146:2957-29742023Visualizing reactive astrocyte-neuron interaction in Alzheimer's disease using 11C-acetate and 18F-FDG.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMin-Ho Nam,Hae Young Ko,Dongwoo Kim,Sangwon Lee,Yongmin Mason Park,Seung Jae Hyeon,Woojin Won,Jee-In Chung,Seon Yoo Kim,Han Hee Jo,Kyeong Taek Oh,Young-Eun Han,Gwan-Ho Lee,Yeon Ha Ju,Hyowon Lee,Hyunjin Kim,Jaejun Heo,Mridula Bhalla,Ki Jung Kim,Jea Kwon,Thor D Stein,Mingyu Kong,Hyunbeom Lee,Seung Eun Lee,Soo-Jin Oh,Joong-Hyun Chun,Mi-Ae Park,Ki Duk Park,Hoon Ryu,Mijin Yun,C Justin LeePubMed 37062541
- Scientific reports 13:25352023Resistance training restores skeletal muscle atrophy and satellite cell content in an animal model of Alzheimer's disease.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMasoud Rahmati,Mohammad Shariatzadeh Joneydi,Ai Koyanagi,Guang Yang,Bingzhou Ji,Seung Won Lee,Dong Keon Yon,Lee Smith,Jae Il Shin,Yusheng LiPubMed 36781881
- Frontiers in pharmacology 13:10583582022Ursolic acid and rosmarinic acid ameliorate alterations in hippocampal neurogenesis and social memory induced by amyloid beta in mouse model of Alzheimer's disease.Applications:Unspecified applicationReactive species:Unspecified reactive speciesFatima Javed Mirza,Saadia ZahidPubMed 36618920
- Journal of neurochemistry 165:809-8262022Leptin-based hexamers facilitate memory and prevent amyloid-driven AMPA receptor internalisation and neuronal degeneration.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGayle Doherty,Alison Holiday,Yasaman Malekizadeh,Cosmin Manolescu,Stephen Duncan,Iona Flewitt,Kirsty Hamilton,Beth MacLeod,James A Ainge,Jenni HarveyPubMed 36444683
- Pharmaceuticals (Basel, Switzerland) 15:2022Protofibrillar Amyloid Beta Modulation of Recombinant hCaV2.2 (N-Type) Voltage-Gated Channels.Applications:Unspecified applicationReactive species:Unspecified reactive speciesEleni Kaisis,Laura J Thei,Gary J Stephens,Mark L DallasPubMed 36558910
- Frontiers in aging neuroscience 14:9603142022Inhibiting amyloid beta (1-42) peptide-induced mitochondrial dysfunction prevents the degradation of synaptic proteins in the entorhinal cortex.Applications:Unspecified applicationReactive species:Unspecified reactive speciesOlayemi Joseph Olajide,Claudia La Rue,Andreas Bergdahl,Clifton Andrew ChapmanPubMed 36275011
- Molecular therapy. Methods & clinical development 27:272-2802022Intravenous immunoglobulin prevents peripheral liver transduction of intrathecally delivered AAV vectors.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMakoto Horiuchi,Christian J Hinderer,Jenny A Greig,Cecilia Dyer,Elizabeth L Buza,Peter Bell,Jessica A Chichester,Peter M Hayashi,Hanying Yan,Tamara Goode,James M WilsonPubMed 36320416
Key facts
- CAS number
- 107761-42-2
- Purity
- > 95%
- Form
- Solid
- Molecular weight
- 4514 Da
- Molecular formula
- C203H311N55O60S
- PubChem identifier
- 57339251
- Nature
- Synthetic
Recommended products
Beta-amyloid peptide (1-42) (human) is with purity of > 95%.
- Reconstitute with PBS at 1 mg/mL
Key facts
- CAS number
- 107761-42-2
- Purity
- > 95%
- Form
- Solid
- Molecular weight
- 4514 Da
- Molecular formula
- C203H311N55O60S
- PubChem identifier
- 57339251
- Nature
- Synthetic
- Solubility
Solubility is batch-dependent. Please refer to the Protocol Booklet and the batch-specific CoA for more information.
- Biochemical name
- Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala
- Canonical SMILES
- CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(C(C)C)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O
- Isomeric SMILES
- CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)O)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC3=CNC=N3)NC(=O)[C@H](CC4=CNC=N4)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC5=CC=C(C=C5)O)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC6=CNC=N6)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC7=CC=CC=C7)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)N
- InChI
- InChI=1S/C203H311N55O60S/c1-28-106(20)164(195(310)220-91-149(267)228-130(71-98(4)5)181(296)238-129(66-70-319-27)179(294)251-158(100(8)9)193(308)218-87-146(264)215-88-151(269)250-160(102(12)13)198(313)255-163(105(18)19)199(314)258-165(107(21)29-2)200(315)227-112(26)202(317)318)257-201(316)166(108(22)30-3)256-169(284)109(23)224-147(265)89-216-171(286)122(51-40-42-67-204)233-188(303)139(81-145(208)263)244-192(307)143(94-260)230-150(268)92-219-194(309)159(101(10)11)252-191(306)141(83-157(280)281)245-177(292)127(60-64-153(272)273)232-168(283)111(25)226-180(295)133(73-113-45-34-31-35-46-113)241-184(299)135(75-115-49-38-33-39-50-115)247-196(311)162(104(16)17)254-190(305)131(72-99(6)7)239-173(288)123(52-41-43-68-205)234-175(290)125(58-62-144(207)262)236-185(300)136(77-117-84-211-95-221-117)243-187(302)138(79-119-86-213-97-223-119)248-197(312)161(103(14)15)253-178(293)128(61-65-154(274)275)237-182(297)132(76-116-54-56-120(261)57-55-116)229-148(266)90-217-172(287)142(93-259)249-189(304)140(82-156(278)279)246-186(301)137(78-118-85-212-96-222-118)242-174(289)124(53-44-69-214-203(209)210)235-183(298)134(74-114-47-36-32-37-48-114)240-176(291)126(59-63-152(270)271)231-167(282)110(24)225-170(285)121(206)80-155(276)277/h31-39,45-50,54-57,84-86,95-112,121-143,158-166,259-261H,28-30,40-44,51-53,58-83,87-94,204-206H2,1-27H3,(H2,207,262)(H2,208,263)(H,211,221)(H,212,222)(H,213,223)(H,215,264)(H,216,286)(H,217,287)(H,218,308)(H,219,309)(H,220,310)(H,224,265)(H,225,285)(H,226,295)(H,227,315)(H,228,267)(H,229,266)(H,230,268)(H,231,282)(H,232,283)(H,233,303)(H,234,290)(H,235,298)(H,236,300)(H,237,297)(H,238,296)(H,239,288)(H,240,291)(H,241,299)(H,242,289)(H,243,302)(H,244,307)(H,245,292)(H,246,301)(H,247,311)(H,248,312)(H,249,304)(H,250,269)(H,251,294)(H,252,306)(H,253,293)(H,254,305)(H,255,313)(H,256,284)(H,257,316)(H,258,314)(H,270,271)(H,272,273)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,317,318)(H4,209,210,214)/t106-,107-,108-,109-,110-,111-,112-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,158-,159-,160-,161-,162-,163-,164-,165-,166-/m0/s1
- InChIKey
- DZHSAHHDTRWUTF-SIQRNXPUSA-N
- IUPAC name
- (4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-6-amino-1-[[2-[[(2S)-1-[[(2S,3S)-1-[[(2S,3S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(1S)-1-carboxyethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-1-oxohexan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-[[(2S)-2-[[(2S)-2-amino-3-carboxypropanoyl]amino]propanoyl]amino]-5-oxopentanoic acid
- Reconstitution
- reconstitute with PBS at 1mg/mL
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Store under desiccating conditions, The product can be stored for up to 12 months
Product promise
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1 product image
Chemical Structure - beta-Amyloid Peptide (1-42) (human) (ab120301)
2D chemical structure image of ab120301, beta-Amyloid Peptide (1-42) (human)
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Product protocols
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