Betamethasone valerate, Glucocorticoid; immunomodulator
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MW 476.6 Da, Purity >98%. Glucocorticoid. Major steroid hormone. Anti-inflammatory and immunosuppresive effects. Active in vivo.
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AIS, ANDR_HUMAN, AR, AR8, Androgen nuclear receptor variant 2, Androgen receptor, Androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease), BXR, DHTR, Dihydro testosterone receptor, Dihydrotestosterone receptor (DHTR), ERR a, ERR-alpha, ERR1 protein, ERR1_HUMAN, ESRL 1, ESRR A, Estrogen receptor related 1, Estrogen receptor-like 1, Estrogen-related receptor alpha, Estrra, GCCR, GCRST, GCR_HUMAN, GR, Glucocorticoid receptor, Grl1, HUMARA, HYSP1, IMD42, KD, Kennedy disease (KD), MGC129539, NR1B1, NR1F3, NR1I2_HUMAN, NR3B1, NR3C3, NR3C4, Nuclear mitotic apparatus protein retinoic acid receptor alpha fusion protein, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group B member 1, Nuclear receptor subfamily 1 group F member 3, Nuclear receptor subfamily 1 group I member 2, Nuclear receptor subfamily 3 group B member 1, Nuclear receptor subfamily 3 group C member 1, Nuclear receptor subfamily 3 group C member 3, Nuclear receptor subfamily 3 group C member 4, Nuclear receptor subfamily 3 group C member 4 (NR3C4), Nucleophosmin retinoic acid receptor alpha fusion protein NPM RAR long form, ONR 1, OTTHUMP00000215173, OTTHUMP00000215174, OTTHUMP00000215175, Orphan nuclear receptor PAR 1, Orphan nuclear receptor PXR, PAR, PAR q, PGR, PR, PRA, PRB, PRGR_HUMAN, PRR, Pregnane X receptor, Progesterone receptor, Progestin receptor form A, Progestin receptor form B, RAR, RAR related orphan nuclear receptor variant 2, RAR related orphan receptor C, isoform a, RAR related orphan receptor gamma, RAR-alpha, RAR-related orphan receptor C, RARA_HUMAN, RARalpha1, RORG_HUMAN, RZR GAMMA, RZRG, Retinoic acid binding receptor gamma, Retinoic acid nuclear receptor alpha variant 1, Retinoic acid nuclear receptor alpha variant 2, Retinoic acid receptor alpha, Retinoic acid receptor alpha polypeptide, Retinoid-related orphan receptor-gamma, Rorc, SBMA, SMAX1, SXR, Spinal and bulbar muscular atrophy, Spinal and bulbar muscular atrophy (SBMA), Steroid and xenobiotic receptor, Steroid hormone receptor ERR1, TFM, TOR, Testicular Feminization (TFM), androgen receptor splice variant 4b, estrogen receptor related receptor alpha, glucocorticoid nuclear receptor variant 1, hERR1, nr3c1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), pregnane X nuclear receptor variant 2
- Chemical Structure
Lab
Chemical Structure - Betamethasone valerate, Glucocorticoid; immunomodulator (AB141280)
2D chemical structure image of ab141280, Betamethasone valerate, Glucocorticoid; immunomodulator
Properties and storage information
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Appropriate long-term storage conditions
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
These nuclear receptors mediate responses to steroid hormones retinoids and other signaling molecules. They often form complexes with coactivators or corepressors to fine-tune gene transcription. GR modulates immune response and metabolism PR regulates reproductive functions AR and RARα play roles in cell differentiation and proliferation. PXR is a master regulator in xenobiotic metabolism while ERRα influences energy metabolism. RORγ is involved in circadian rhythm and immune functions especially in T cell development.
Pathways
Nuclear receptors such as GR and PXR play essential roles in the glucocorticoid signaling and xenobiotic detoxification pathways. GR is closely associated with metabolic pathways and responds to glucocorticoids like betamethasone while PXR activates genes involved in drug metabolism. AR and PR are integral to steroid signaling pathways. ERRα contributes to mitochondrial biogenesis pathways. RORγ interacts with pathways involved in immune system regulation. These receptors often interact with proteins such as coactivators and other nuclear receptors influencing broad cellular functions and responses.
Product promise
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