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AB141233

Bezafibrate, Pan-PPAR agonist

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MW 361.8 Da, Purity >99%. Pan-PPAR agonist (EC50 values are 50, 60 and 20 μM at PPARα, PPARγ and PPARδ human receptors respectively). More efficient than fenofibrate (ab120832) in reducing body weight and blood glucose. Antidiabetic and antihyperlipidemic effects.

View Alternative Names

FAAR, FABP 1, FABP 2, FABPI_HUMAN, FABPL_HUMAN, Fatty acid binding protein 1 liver, Fatty acid binding protein 2 intestinal, Fatty acid binding protein intestinal, Fatty acid-binding protein, Fatty acid-binding protein 1, Fatty acid-binding protein 2, Fatty acid-binding protein liver, I-FABP, Intestinal fatty acid binding protein 2, Intestinal-type fatty acid-binding protein, L-FABP, Liver-type fatty acid-binding protein, MGC133132, MGC2237, MGC2452, MGC3931, NR1C1, NR1C2, NR1C3, NUC1, NUCI, NUCII, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member 1, Nuclear receptor subfamily 1 group C member 2, Nuclear receptor subfamily 1 group C member 3, OTTHUMP00000163925, OTTHUMP00000197740, OTTHUMP00000197741, PPAR, PPAR-alpha, PPAR-beta, PPAR-delta, PPAR-gamma, PPAR-鑴, PPARA_HUMAN, PPARB, PPARD_HUMAN, PPARG2, PPARG_HUMAN, Peroxisome proliferative activated receptor alpha, Peroxisome proliferative activated receptor delta, Peroxisome proliferator activated receptor gamma 2, Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor beta, Peroxisome proliferator-activated receptor beta (PPAR-beta), Peroxisome proliferator-activated receptor delta, Peroxisome proliferator-activated receptor gamma, hPPAR, intestinal, intestinal FABP

1 Images
Chemical Structure - Bezafibrate, Pan-PPAR agonist (AB141233)
  • Chemical Structure

Lab

Chemical Structure - Bezafibrate, Pan-PPAR agonist (AB141233)

2D chemical structure image of ab141233, Bezafibrate, Pan-PPAR agonist

Key facts

CAS number

41859-67-0

Purity

>99%

Form

Solid

form

Molecular weight

361.8 Da

Molecular formula

C<sub>1</sub><sub>9</sub>H<sub>2</sub><sub>0</sub>ClNO<sub>4</sub>

PubChem

39042

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 50 mM

Biochemical name

Bezafibrate

Biological description

Pan-PPAR agonist (EC50 values are 50, 60 and 20 μM at PPARα, PPARγ and PPARδ human receptors respectively). More efficient than fenofibrate (ab120832) in reducing body weight and blood glucose. Antidiabetic and antihyperlipidemic effects.

Canonical smiles

CC(C)(C(=O)O)OC1=CC=C(C=C1)CCNC(=O)C2=CC=C(C=C2)Cl

InChi

InChI=1S/C19H20ClNO4/c1-19(2,18(23)24)25-16-9-3-13(4-10-16)11-12-21-17(22)14-5-7-15(20)8-6-14/h3-10H,11-12H2,1-2H3,(H,21,22)(H,23,24)

InChiKey

IIBYAHWJQTYFKB-UHFFFAOYSA-N

IUPAC Name

2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months

Product protocols

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