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AB141233

Bezafibrate, Pan-PPAR agonist

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MW 361.8 Da, Purity >99%. Pan-PPAR agonist (EC50 values are 50, 60 and 20 μM at PPARα, PPARγ and PPARδ human receptors respectively). More efficient than fenofibrate (ab120832) in reducing body weight and blood glucose. Antidiabetic and antihyperlipidemic effects.
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Chemical Structure - Bezafibrate, Pan-PPAR agonist (AB141233)
  • Chemical Structure

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Chemical Structure - Bezafibrate, Pan-PPAR agonist (AB141233)

2D chemical structure image of ab141233, Bezafibrate, Pan-PPAR agonist

Key facts

CAS number

41859-67-0

Purity

>99%

Form

Solid

form

Molecular weight

361.8 Da

Molecular formula

C<sub>1</sub><sub>9</sub>H<sub>2</sub><sub>0</sub>ClNO<sub>4</sub>

PubChem

39042

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 50 mM

Biochemical name

Bezafibrate

Biological description

Pan-PPAR agonist (EC50 values are 50, 60 and 20 μM at PPARα, PPARγ and PPARδ human receptors respectively). More efficient than fenofibrate (ab120832) in reducing body weight and blood glucose. Antidiabetic and antihyperlipidemic effects.

Canonical smiles

CC(C)(C(=O)O)OC1=CC=C(C=C1)CCNC(=O)C2=CC=C(C=C2)Cl

InChi

InChI=1S/C19H20ClNO4/c1-19(2,18(23)24)25-16-9-3-13(4-10-16)11-12-21-17(22)14-5-7-15(20)8-6-14/h3-10H,11-12H2,1-2H3,(H,21,22)(H,23,24)

InChiKey

IIBYAHWJQTYFKB-UHFFFAOYSA-N

IUPAC Name

2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid

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Complementary Products

Biochemicals

AB120832

Fenofibrate, PPAR-alpha agonist

Chemical Structure - Fenofibrate, PPAR-alpha agonist (AB120832)

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Biochemicals

AB120124

2-APB, Ca2+ release modulator

Functional Studies - 2-APB, Ca2+ release modulator (AB120124)

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Primary Antibodies

AB128860

Anti-I-FABP antibody [EPR7136]

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-I-FABP antibody [EPR7136] (AB128860)

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Assay Kits

AB234566

Human FABP2 ELISA Kit

Recombinant|SimpleStep

ELISA - Human FABP2 ELISA Kit (AB234566)

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
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Product protocols

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