Bindarit, CCL2, CCL7 and CCL8 inhibitor

Key facts

CAS number

130641-38-2

Purity

>99%

Form

Solid

form

Molecular weight

324.4 Da

Molecular formula

C₁₉H₂₀N₂O₃

PubChem

71354

Nature

Synthetic

Solubility

Soluble in ethanol to 25 mM

Soluble in DMSO to 100 mM

Biochemical name

Bindarit

Biological description

CCL2, CCL7 and CCL8 inhibitor. Anti-inflammatory agent. Shows antiproliferative, antimetastatic and antitumor effects in vivo. Prevents neuroinflammation in vivo. Orally active.

Canonical smiles

CC(C)(C(=O)O)OCC1=NN(C2=CC=CC=C21)CC3=CC=CC=C3

InChi

InChI=1S/C19H20N2O3/c1-19(2,18(22)23)24-13-16-15-10-6-7-11-17(15)21(20-16)12-14-8-4-3-5-9-14/h3-11H,12-13H2,1-2H3,(H,22,23)

InChiKey

MTHORRSSURHQPZ-UHFFFAOYSA-N

IUPAC Name

2-[(1-benzylindazol-3-yl)methoxy]-2-methylpropanoic acid