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MW 441.2 Da, Purity >99%. Potent and selective allosteric inhibitor of MEK1/2. Orally bioavailable. Achieve your results faster with highly validated, pure and trusted compounds.

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Key facts

CAS number
606143-89-9
Purity
> 99
Form
Solid
Molecular weight
441.2 Da
Molecular formula
C17H15BrF2N4O3
PubChem identifier
10288191
Nature
Synthetic

Target data

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MW 441.2 Da, Purity >99%. Potent and selective allosteric inhibitor of MEK1/2. Orally bioavailable. Achieve your results faster with highly validated, pure and trusted compounds.

Key facts

Purity
> 99
PubChem identifier
10288191
Solubility

Soluble in DMSO to 50 mM.

Biochemical name
Binimetinib
Biological description

Potent and selective allosteric inhibitor of MEK1/2. Orally bioavailable.

Canonical SMILES
CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)F)C(=O)NOCCO
InChI
InChI=1S/C17H15BrF2N4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)
InChIKey
ACWZRVQXLIRSDF-UHFFFAOYSA-N
IUPAC name
6-(4-bromo-2-fluoroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions

Notes

Solutions in DMSO may be stored at -20°C for up to 3 months.

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