JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB254449

Binimetinib, MEK1/2 inhibitor

Be the first to review this product! Submit a review

|

(0 Publication)

MW 441.2 Da, Purity >99%. Potent and selective allosteric inhibitor of MEK1/2. Orally bioavailable. Achieve your results faster with highly validated, pure and trusted compounds.
1 Images
Chemical Structure - Binimetinib, MEK1/2 inhibitor (AB254449)
  • Chemical Structure

Supplier Data

Chemical Structure - Binimetinib, MEK1/2 inhibitor (AB254449)

2D chemical structure image of ab254449, Binimetinib, MEK1/2 inhibitor

Key facts

CAS number

606143-89-9

Purity

>99%

Form

Solid

form

Molecular weight

441.2 Da

Molecular formula

C<sub>1</sub><sub>7</sub>H<sub>1</sub><sub>5</sub>BrF<sub>2</sub>N<sub>4</sub>O<sub>3</sub>

PubChem

10288191

Nature

Synthetic

Solubility

Soluble in DMSO to 50 mM

Biochemical name

Binimetinib

Biological description

Potent and selective allosteric inhibitor of MEK1/2. Orally bioavailable.

Canonical smiles

CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)F)C(=O)NOCCO

InChi

InChI=1S/C17H15BrF2N4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)

InChiKey

ACWZRVQXLIRSDF-UHFFFAOYSA-N

IUPAC Name

6-(4-bromo-2-fluoroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide

style
left-column

Product details

Solutions in DMSO may be stored at -20°C for up to 3 months.
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions
style
left-column
style
left-column
style
left-column

Product protocols

style
left-column
style
left-column
style
right-column

Complementary Products

Proteins & Peptides

AB215606

Recombinant Human Mesothelin protein (His tag)

  • 0
  • 0
Biochemicals

AB141024

AM 80, retinoic acid receptor alpha/beta (RAR alpha/beta) agonist

Chemical Structure - AM 80, retinoic acid receptor alpha/beta (RAR alpha/beta) agonist (AB141024)

  • 0
  • 0
Biochemicals

AB254451

BI-D1870, RSK Inhibitor

Chemical Structure - BI-D1870, RSK Inhibitor (AB254451)

  • 0
  • 0
Assay Kits

AB216168

Human Mesothelin ELISA Kit

Recombinant|SimpleStep

ELISA - Human Mesothelin ELISA Kit (AB216168)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com