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AB141452

Blasticidin S hydrochloride, Nucleoside antibiotic

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(1 Publication)

MW 458.9 Da, Purity >98%. Broad spectrum amino nucleoside antibiotic agent similar to puromycin. Inhibits protein biosynthesis at both prokaryotic and eukaryotic ribosomes.
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Chemical Structure - Blasticidin S hydrochloride, Nucleoside antibiotic (AB141452)
  • Chemical Structure

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Chemical Structure - Blasticidin S hydrochloride, Nucleoside antibiotic (AB141452)

2D chemical structure image of ab141452, Blasticidin S hydrochloride, Nucleoside antibiotic

Key facts

CAS number

3513-03-9

Purity

>98%

Form

Solid

form

Molecular weight

458.9 Da

Molecular formula

C<sub>1</sub><sub>7</sub>H<sub>2</sub><sub>7</sub>ClN<sub>8</sub>O<sub>5</sub>

PubChem

25078183

Nature

Synthetic

Solubility

Soluble in water to 50 mM

Biochemical name

Blasticidine S hydrochloride

Biological description

Broad spectrum amino nucleoside antibiotic agent similar to puromycin. Inhibits protein biosynthesis at both prokaryotic and eukaryotic ribosomes.

Canonical smiles

CN(CCC(CC(=O)NC1C=CC(OC1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl

Isomeric smiles

CN(CC[C@H](CC(=O)N[C@H]1C=C[C@@H](O[C@@H]1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl

InChi

InChI=1S/C17H26N8O5.ClH/c1-24(16(20)21)6-4-9(18)8-12(26)22-10-2-3-13(30-14(10)15(27)28)25-7-5-11(19)23-17(25)29;/h2-3,5,7,9-10,13-14H,4,6,8,18H2,1H3,(H3,20,21)(H,22,26)(H,27,28)(H2,19,23,29);1H/t9-,10+,13-,14+;/m1./s1

InChiKey

YQXYQOXRCNEATG-ZAYJLJTISA-N

IUPAC Name

(2S,3S,6R)-3-[[(3R)-3-amino-5-[carbamimidoyl(methyl)amino]pentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2H-pyran-2-carboxylic acid;hydrochloride

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Complementary Products

Biochemicals

AB141453

Puromycin dihydrochloride, Protein biosynthesis inhibitor

Chemical Structure - Puromycin dihydrochloride, Protein biosynthesis inhibitor (AB141453)

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Biochemicals

AB144261

G 418 sulfate (Geneticin sulfate), Aminoglycoside antibiotic agent

Chemical Structure - G 418 sulfate (Geneticin sulfate), Aminoglycoside antibiotic agent (AB144261)

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Biochemicals

AB286934

Hygromycin B

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  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 1859 Blasticidin S Hydrochloride. 1859-100 is the same size as the 100 mg size of ab141452.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 16:2923 PubMed40133256

2025

The ER-phagy receptor FAM134B is targeted by Salmonella Typhimurium to promote infection.

Applications

Unspecified application

Species

Unspecified reactive species

Damián Gatica,Reham M Alsaadi,Rayan El Hamra,Boran Li,Rudolf Mueller,Makoto Miyazaki,Qiming Sun,Subash Sad,Ryan C Russell
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