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MW 350.4 Da, Purity >98%. Cell-permeable Wnt signaling activator. Induces β-catenin and TCF-dependent transcriptional activity (EC50 = 0.7 μM). Activates Wnt without inhibiting GSK-3β.Shows developmental effects in vivo. .

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Images

Chemical Structure - BML 284, Wnt signaling activator (AB145241), expandable thumbnail

Publications

Key facts

CAS number
853220-52-7
Purity
> 98%
Molecular weight
350.4 Da
Molecular formula
C19H18N4O3
PubChem identifier
11210285
Nature
Synthetic

Target data

Recommended products

MW 350.4 Da, Purity >98%. Cell-permeable Wnt signaling activator. Induces β-catenin and TCF-dependent transcriptional activity (EC50 = 0.7 μM). Activates Wnt without inhibiting GSK-3β.Shows developmental effects in vivo. .

Key facts

Purity
> 98%
PubChem identifier
11210285
Solubility

Soluble in ethanol to 100 mM.

Soluble in DMSO to 100 mM.

Biochemical name
N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine
Biological description

Cell-permeable Wnt signaling activator. Induces β-catenin and TCF-dependent transcriptional activity (EC50 = 0.7 μM). Activates Wnt without inhibiting GSK-3β.Shows developmental effects in vivo.

Canonical SMILES
COC1=CC=CC(=C1)C2=CC(=NC(=N2)N)NCC3=CC4=C(C=C3)OCO4
InChI
InChI=1S/C19H18N4O3/c1-24-14-4-2-3-13(8-14)15-9-18(23-19(20)22-15)21-10-12-5-6-16-17(7-12)26-11-25-16/h2-9H,10-11H2,1H3,(H3,20,21,22,23)
InChIKey
FABQUVYDAXWUQP-UHFFFAOYSA-N
IUPAC name
4-N-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

Product promise

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Terms & Conditions.

1 product image

  • Chemical Structure - BML 284, Wnt signaling activator (ab145241), expandable thumbnail

    Chemical Structure - BML 284, Wnt signaling activator (ab145241)

    2D chemical structure image of ab145241, BML 284, Wnt signaling activator

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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