AB120520
BMY 7378 dihydrochloride, 5-HT1A partial agonist. alpha adrenoceptor antagonist.
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(1 Publication)
MW 458.43 g/mol, Purity >99%. 5-HT1A partial agonist (IC50 = 0.8 nM). Potent and selective α1D adrenoceptor antagonist (Ki values are 2, 600 and 800 nM at α1D, α1B and α1A receptors, respectively). Shows antihypertensive activity.
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- Chemical Structure
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Chemical Structure - BMY 7378 dihydrochloride, 5-HT1A partial agonist. alpha adrenoceptor antagonist. (AB120520)
2D chemical structure image of ab120520, BMY 7378 dihydrochloride, 5-HT1A partial agonist. alpha adrenoceptor antagonist.
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Properties and storage information
Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
Publications (1)
Recent publications for all applications. Explore the full list and refine your search
Nature communications 16:5215 PubMed40473608
2025
A gatekeeper sympathetic control of lacrimal tear secretion and dry eye onset through the NA-Adra1a-Ucp2 pathway.
Applications
Unspecified application
Species
Unspecified reactive species
Mingli Qu,Qun Wang,Xiaofei Bai,Jing Feng,Sai Zhang,Yangyang Zhang,Qing Chen,Hai Zhu,Hengrui Zhang,Qunqin Guo,Bin Zhang,Shengqian Dou,Yujie Qiao,Hongwei Wang,Yihai Cao,Lixin Xie,Qingjun Zhou
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