Skip to main content

MW 458.43 g/mol, Purity >99%.

5-HT1A partial agonist (IC50 = 0.8 nM). Potent and selective α1D adrenoceptor antagonist (Ki values are 2, 600 and 800 nM at α1D, α1B and α1A receptors, respectively). Shows antihypertensive activity.

Be the first to review this product! Submit a review

Images

Chemical Structure - BMY 7378 dihydrochloride, 5-HT1A partial agonist. alpha adrenoceptor antagonist. (AB120520), expandable thumbnail

Key facts

CAS number
21102-95-4
Purity
> 99%
Form
Solid
Molecular weight
458.43 g/mol
Nature
Synthetic

Target data

Recommended products

MW 458.43 g/mol, Purity >99%.

5-HT1A partial agonist (IC50 = 0.8 nM). Potent and selective α1D adrenoceptor antagonist (Ki values are 2, 600 and 800 nM at α1D, α1B and α1A receptors, respectively). Shows antihypertensive activity.

Key facts

Purity
> 99%
Solubility

Soluble in water to 100 mM.

Biological description

5-HT1A partial agonist (IC50 = 0.8 nM). Potent and selective α1D adrenoceptor antagonist (Ki values are 2, 600 and 800 nM at α1D, α1B and α1A receptors, respectively). Shows antihypertensive activity.

IUPAC name
8-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspirol[4,5]decane-7,9-dione dihydrochloride

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • Chemical Structure - BMY 7378 dihydrochloride, 5-HT1A partial agonist. alpha adrenoceptor antagonist. (ab120520), expandable thumbnail

    Chemical Structure - BMY 7378 dihydrochloride, 5-HT1A partial agonist. alpha adrenoceptor antagonist. (ab120520)

    2D chemical structure image of ab120520, BMY 7378 dihydrochloride, 5-HT1A partial agonist. alpha adrenoceptor antagonist.

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com