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AB144214

bpV(HOpic), PTP and PTEN inhibitor

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MW 347.24 g/mol, Purity >95%. Inhibits PTP (IC50 = 4-25 μM) and PTEN (IC50 = 14 nM). Insulin mimetic. Enhances PI3K/Akt signaling and possibly prevents myocardium from ischemia-reperfusion injury. Active in vitro.
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Chemical Structure - bpV(HOpic), PTP and PTEN inhibitor (AB144214)
  • Chemical Structure

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Chemical Structure - bpV(HOpic), PTP and PTEN inhibitor (AB144214)

2D chemical structure image of ab144214, bpV(HOpic), PTP and PTEN inhibitor

Key facts

CAS number

722494-26-0

Purity

>95%

Form

Solid

form

Molecular weight

347.24 g/mol

Molecular formula

C<sub>6</sub>H<sub>4</sub>K<sub>2</sub>NO<sub>8</sub>V

Nature

Synthetic

Solubility

Soluble in DMSO

Biological description

Inhibits PTP (IC50 = 4-25 μM) and PTEN (IC50 = 14 nM). Insulin mimetic. Enhances PI3K/Akt signaling and possibly prevents myocardium from ischemia-reperfusion injury. Active in vitro.

InChi

InChI=1S/C6H5NO3.2K.2O2.O.V/c8-4-1-2-5(6(9)10)7-3-4;;;2*1-2;;/h1-3,8H,(H,9,10);;;;;;/q;2*+1;2*-2;;+3/p-1

InChiKey

IZLHQXYPQCZJAG-UHFFFAOYSA-M

IUPAC Name

Dipotassium bisperoxo(5-hydroxypyridine-2-carboxyl)oxovanadate (V)

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Complementary Products

Biochemicals

AB141407

BIX 01294, histone methyltransferase inhibitor

Chemical Structure - BIX 01294, histone methyltransferase inhibitor (AB141407)

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Biochemicals

AB141416

Pepstatin A, aspartic protease inhibitor

Chemical Structure - Pepstatin A, aspartic protease inhibitor (AB141416)

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Primary Antibodies

AB253017

Anti-HIP14 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HIP14 antibody (AB253017)

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Biochemicals

AB141404

Leupeptin hemisulfate, serine/cysteine protease inhibitor

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Product details

This product is not stable in water; immediately upon dissolution decomposition starts to occur. Decomposition in dry DMSO has also been observed but at a slower rate.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
It is important to note that this product is reported to be light sensitive|Store in the dark|Store under desiccating conditions
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Product protocols

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