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AB141437

bpV(pic), Protein phosphotyrosine phosphatase (PTP) and PTEN inhibitor

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(1 Publication)

MW 372.31 Da, Purity >90%. Potent protein phosphotyrosine phosphatase (PTP) and PTEN inhibitor. Also activates insulin receptor kinase (IRK). Apoptosis inhibitor.
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Chemical Structure - bpV(pic), Protein phosphotyrosine phosphatase (PTP) and PTEN inhibitor (AB141437)
  • Chemical Structure

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Chemical Structure - bpV(pic), Protein phosphotyrosine phosphatase (PTP) and PTEN inhibitor (AB141437)

2D chemical structure image of ab141437, bpV(pic), Protein phosphotyrosine phosphatase (PTP) and PTEN inhibitor

Key facts

CAS number

148556-27-8

Purity

>90%

Form

Solid

form

Molecular weight

372.31 Da

Molecular formula

C<sub>6</sub>H<sub>1</sub><sub>3</sub>K<sub>2</sub>NO<sub>9</sub>V

PubChem

16760324

Nature

Synthetic

Solubility

Soluble in DMSO

Soluble in water

Biochemical name

Dipotassium Bisperoxo(picolinato)oxovanadate (V)

Biological description

Potent protein phosphotyrosine phosphatase (PTP) and PTEN inhibitor. Also activates insulin receptor kinase (IRK). Apoptosis inhibitor.

Canonical smiles

C1=CC=NC(=C1)C(=O)[O-].O.O.[OH-].OO.OO.[K+].[K+].[V]

InChi

InChI=1S/C6H5NO2.2K.2H2O2.3H2O.V/c8-6(9)5-3-1-2-4-7-5;;;2*1-2;;;;/h1-4H,(H,8,9);;;2*1-2H;3*1H2;/q;2*+1;;;;;;/p-2

InChiKey

WVBWLFCUGGODSA-UHFFFAOYSA-L

IUPAC Name

dipotassium;hydrogen peroxide;pyridine-2-carboxylate;vanadium;hydroxide;dihydrate

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Complementary Products

Biochemicals

AB141416

Pepstatin A, aspartic protease inhibitor

Chemical Structure - Pepstatin A, aspartic protease inhibitor (AB141416)

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Biochemicals

AB141439

VO-OHpic trihydrate, PTEN inhibitor

Chemical Structure - VO-OHpic trihydrate, PTEN inhibitor (AB141439)

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Biochemicals

AB142181

Cathepsin G Inhibitor, cathepsin G inhibitor

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Biochemicals

AB141404

Leupeptin hemisulfate, serine/cysteine protease inhibitor

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 1794 bpV(pic). 1794-5 is the same size as the 5 mg size of ab141437.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Neuroscience letters 676:78-84 PubMed29649487

2018

Expression patterns and role of PTEN in rat peripheral nerve development and injury.

Applications

Unspecified application

Species

Unspecified reactive species

Hui Chen,Jianping Xiang,Junxia Wu,Bo He,Tao Lin,Qingtang Zhu,Xiaolin Liu,Canbin Zheng
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