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MW 366.4 Da. p90 ribosomal S6 kinase RSK inhibitor (IC50 values are 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively). Upregulates insulin expression in pancreatic α-cells. Shows reprogramming effects in terminally differentiated cells.

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Images

Chemical Structure - BRD-7389, p90 ribosomal S6 kinase RSK inhibitor (AB146161), expandable thumbnail

Key facts

Form
Solid
Molecular weight
366.4 Da
Molecular formula
C24H18N2O2
PubChem identifier
24870634
Nature
Synthetic

Target data

Recommended products

MW 366.4 Da. p90 ribosomal S6 kinase RSK inhibitor (IC50 values are 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively). Upregulates insulin expression in pancreatic α-cells. Shows reprogramming effects in terminally differentiated cells.

Key facts

PubChem identifier
24870634
Solubility

Soluble in DMSO to 100 mM.

Biochemical name
16-(2-Phenylethylamino)-14-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(16),2,4,6,9,11,13-heptaene-8,15-dione
Biological description

p90 ribosomal S6 kinase RSK inhibitor (IC50 values are 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively). Upregulates insulin expression in pancreatic α-cells. Shows reprogramming effects in terminally differentiated cells.

Canonical SMILES
C1=CC=C(C=C1)CCNC2=C3C4C(=NC2=O)C=CC=C4C(=O)C5=CC=CC=C53
InChI
InChI=1S/C24H18N2O2/c27-23-17-10-5-4-9-16(17)21-20-18(23)11-6-12-19(20)26-24(28)22(21)25-14-13-15-7-2-1-3-8-15/h1-12,20,25H,13-14H2
InChIKey
QVEVXIXBUORVGE-UHFFFAOYSA-N
IUPAC name
16-(2-phenylethylamino)-14-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(16),2,4,6,9,11,13-heptaene-8,15-dione

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

Product promise

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1 product image

  • Chemical Structure - BRD-7389, p90 ribosomal S6 kinase RSK inhibitor (ab146161), expandable thumbnail

    Chemical Structure - BRD-7389, p90 ribosomal S6 kinase RSK inhibitor (ab146161)

    2D chemical structure image of ab146161, BRD-7389, p90 ribosomal S6 kinase RSK inhibitor

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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