AB273384
MW 410.4 Da, Purity >95%. Potent class I PI3K inhibitor, blocking both p110α and p110β (IC₅₀ = 52 nM and 166 nM, respectively) in vitro. At 5 μM, prevents the growth of assorted cancer cell lines and inhibits tumor growth in vivo. Reduced effect against class III PI3K Vps34 and mammalian target of rapamycin (mTOR).
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- Chemical Structure
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Chemical Structure - Buparlisib (BKM120) (AB273384)
Chemical structure of Buparlisib (BKM120), 944396-07-0
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Product details
This product is manufactured by BioVision, an Abcam company and was previously called 2619 NVP-BKM120. 2619-25 is the same size as the 25 mg size of ab273384.
Protect from air.
Properties and storage information
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
It is important to note that this is air sensitive and impurities can occur as a result of air oxidation|Store in the dark
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