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MW 276.2 g/mol, Purity >98%. Non-selective dopamine and norepinephrine transporter (DAT/NET) inhibitor (Ki values are 1.4, 2.8 and 45 μM for NET, DAT and SERT transporters, respectively). Nicotinic acetylcholine receptor (nAChR) antagonist (IC50 = 1.8 μM at α2β2 receptor). Displays antidepressant activity.

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Images

Chemical Structure - Bupropion hydrochloride, Non-selective DAT/NET inhibitor (AB120534), expandable thumbnail

Publications

Key facts

CAS number

31677-93-7

Purity

> 98%

Form

Solid

Molecular weight

276.2 g/mol

Molecular formula

C13H18ClNOHCl

Nature

Synthetic

Recommended products

MW 276.2 g/mol, Purity >98%. Non-selective dopamine and norepinephrine transporter (DAT/NET) inhibitor (Ki values are 1.4, 2.8 and 45 μM for NET, DAT and SERT transporters, respectively). Nicotinic acetylcholine receptor (nAChR) antagonist (IC50 = 1.8 μM at α2β2 receptor). Displays antidepressant activity.

Key facts

Purity

> 98%

Solubility

Soluble in water to 100 mM. Soluble in DMSO to 100 mM.

Biological description

Non-selective dopamine and norepinephrine transporter (DAT/NET) inhibitor (Ki values are 1.4, 2.8 and 45 μM for NET, DAT and SERT transporters, respectively). Nicotinic acetylcholine receptor (nAChR) antagonist (IC50 = 1.8 μM at α2β2 receptor). Displays antidepressant activity.

IUPAC name

(±)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride

Storage

Shipped at conditions

Ambient - Can Ship with Ice

Appropriate short-term storage conditions

Ambient

Appropriate long-term storage conditions

Ambient

Storage information

Store under desiccating conditions, The product can be stored for up to 12 months

Product promise

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1 product image

  • Chemical Structure - Bupropion hydrochloride, Non-selective DAT/NET inhibitor (ab120534), expandable thumbnail

    Chemical Structure - Bupropion hydrochloride, Non-selective DAT/NET inhibitor (ab120534)

    2D chemical structure image of ab120534, Bupropion hydrochloride, Non-selective DAT/NET inhibitor

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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