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AB120534

Bupropion hydrochloride, Non-selective DAT/NET inhibitor

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MW 276.2 g/mol, Purity >98%. Non-selective dopamine and norepinephrine transporter (DAT/NET) inhibitor (Ki values are 1.4, 2.8 and 45 μM for NET, DAT and SERT transporters, respectively). Nicotinic acetylcholine receptor (nAChR) antagonist (IC50 = 1.8 μM at α2β2 receptor). Displays antidepressant activity.
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Chemical Structure - Bupropion hydrochloride, Non-selective DAT/NET inhibitor (AB120534)
  • Chemical Structure

Lab

Chemical Structure - Bupropion hydrochloride, Non-selective DAT/NET inhibitor (AB120534)

2D chemical structure image of ab120534, Bupropion hydrochloride, Non-selective DAT/NET inhibitor

Key facts

CAS number

31677-93-7

Purity

>98%

Form

Solid

form

Molecular weight

276.2 g/mol

Molecular formula

C<sub>1</sub><sub>3</sub>H<sub>1</sub><sub>8</sub>ClNO.HCl

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Soluble in DMSO to 100 mM

Biological description

Non-selective dopamine and norepinephrine transporter (DAT/NET) inhibitor (Ki values are 1.4, 2.8 and 45 μM for NET, DAT and SERT transporters, respectively). Nicotinic acetylcholine receptor (nAChR) antagonist (IC50 = 1.8 μM at α2β2 receptor). Displays antidepressant activity.

IUPAC Name

(±)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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