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AB141304

BVT 948, Protein tyrosine phosphatase (PTP) inhibitor

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MW 241.24 Da, Purity >99%. Non-competitive, irreversible protein tyrosine phosphatase (PTP) inhibitor (IC50 values are 0.9 (PTP1B), 1.7 (TCPTP), 0.09 (SHP-2), 1.5 (LAR) and 0.7 (YopH) μM). Active in vivo and cell-permeable.
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Chemical Structure - BVT 948, Protein tyrosine phosphatase (PTP) inhibitor (AB141304)
  • Chemical Structure

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Chemical Structure - BVT 948, Protein tyrosine phosphatase (PTP) inhibitor (AB141304)

2D chemical structure image of ab141304, BVT 948, Protein tyrosine phosphatase (PTP) inhibitor

Key facts

CAS number

39674-97-0

Purity

>99%

Form

Solid

form

Formulation

Constituents: 100% 4-Hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione

Molecular weight

241.24 Da

Molecular formula

C<sub>1</sub><sub>4</sub>H<sub>1</sub><sub>1</sub>NO<sub>3</sub>

PubChem

6604934

Nature

Synthetic

Solubility

Soluble in DMSO to 50 mM

Soluble in ethanol to 20 mM

Biochemical name

4-Hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione

Biological description

Non-competitive, irreversible protein tyrosine phosphatase (PTP) inhibitor (IC50 values are 0.9 (PTP1B), 1.7 (TCPTP), 0.09 (SHP-2), 1.5 (LAR) and 0.7 (YopH) μM). Active in vivo and cell-permeable.

Canonical smiles

CC1(C2=C(C3=CC=CC=C3C(=O)C2=O)NC1=O)C

InChi

InChI=1S/C14H11NO3/c1-14(2)9-10(15-13(14)18)7-5-3-4-6-8(7)11(16)12(9)17/h3-6H,1-2H3,(H,15,18)

InChiKey

LLPBUXODFQZPFH-UHFFFAOYSA-N

IUPAC Name

3,3-dimethyl-1H-benzo[g]indole-2,4,5-trione

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Biochemicals

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Biochemicals

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Biochemicals

AB141028

Dextromethorphan hydrobromide, NMDA receptor antagonist

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Primary Antibodies

AB190828

Anti-Hsp60 antibody [EPR18245-93] - Mitochondrial Marker

20ul selling size|RabMAb|Recombinant|Lab Essentials

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Hsp60 antibody [EPR18245-93] - Mitochondrial Marker (AB190828)

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
It is important to note that this product is reported to be light sensitive|Store in the dark|Store under desiccating conditions
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Refer to SDS for further information.

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Product protocols

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Product promise

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