JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB146431

Caged MK 801, NMDA receptor open-channel blocker

Be the first to review this product! Submit a review

|

(0 Publication)

MW 460.49 g/mol, Purity >99%. Caged, potent, selective, non-competitive, irreversible NMDA receptor open-channel blocker. UV-active MK 801 (ab144485, ab120027, ab120028) analog. Shows anticonvulsant effects in vivo. .
1 Images
Chemical Structure - Caged MK 801, NMDA receptor open-channel blocker (AB146431)
  • Chemical Structure

Lab

Chemical Structure - Caged MK 801, NMDA receptor open-channel blocker (AB146431)

2D chemical structure image of ab146431, Caged MK 801, NMDA receptor open-channel blocker

Key facts

CAS number

217176-91-5

Purity

>99%

Form

Solid

form

Molecular weight

460.49 g/mol

Molecular formula

C<sub>2</sub><sub>6</sub>H<sub>2</sub><sub>4</sub>N<sub>2</sub>O<sub>6</sub>

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Biological description

Caged, potent, selective, non-competitive, irreversible NMDA receptor open-channel blocker. UV-active MK 801 (ab144485, ab120027, ab120028) analog. Shows anticonvulsant effects in vivo.

Isomeric smiles

[O-][N+](=O)C5CC(OC)C(OC)CC5COC(=O)N4[C@@H]3CC1CCCCC1[C@@]4(C)C2CCCCC23

InChi

InChI=1S/C26H24N2O6/c1-26-19-10-6-4-8-16(19)12-22(18-9-5-7-11-20(18)26)27(26)25(29)34-15-17-13-23(32-2)24(33-3)14-21(17)28(30)31/h4-11,13-14,22H,12,15H2,1-3H3/t22-,26+/m1/s1

InChiKey

WZDXUEMCALAOAY-GJZUVCINSA-N

IUPAC Name

(5S,10R)-10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine-12-carboxylic acid (4,5-dimethoxy-2-nitrophenyl)methyl ester

style
left-column

Complementary Products

Assay Kits

AB187394

Human TIMP1 ELISA Kit

Recombinant|SimpleStep

ELISA - Human TIMP1 ELISA Kit (AB187394)

  • 0
  • 0
Reagents, Controls & Accessories

AB119211

InstantBlue® Coomassie Protein Stain (ISB1L)

Western blot - InstantBlue® Coomassie Protein Stain (ISB1L) (AB119211)

  • 5
  • 5
Biochemicals

AB144485

(+)-MK 801 maleate (Dizocilpine) (mM/ml), NMDA antagonist

Chemical Structure - (+)-MK 801 maleate (Dizocilpine) (mM/ml), NMDA antagonist (AB144485)

  • 0
  • 0
Assay Kits

AB83389

Glutamate Assay Kit

Functional Studies - Glutamate Assay Kit (AB83389)

  • 4
  • 2
style
left-column
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
It is important to note that this product is reported to be light sensitive|Store in the dark|Store under desiccating conditions
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

|

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

|

Refer to SDS for further information.

style
left-column
style
left-column
style
left-column

Product protocols

style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com