MW 494.52 g/mol, Purity >98%. Trypsin-like protease inhibitor. Reversibly inhibits airway epithelial sodium channel (ENaC) function (IC50 = 50 nM). Inhibits the production of TNF-α and monocyte chemoattractant protein-1 (MCP-1) by monocytes and disrupts proliferation of pancreatic stellate cells in a rat model of pancreatic fibrosis.
Inhibits transmembrane serine protease TMPRSS2 and blocks entry of SARS-Cov-2 into lung cells.
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- Nutrients 14:2022Lipid Raft Integrity and Cellular Cholesterol Homeostasis Are Critical for SARS-CoV-2 Entry into Cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAhmed Bakillah,Fatimah Al Hejji,Abdulrahman Almasaud,Haya Al Jami,Abbas Hawwari,Ali Al Qarni,Jahangir Iqbal,Naif Khalaf AlharbiPubMed 36014919
Key facts
- CAS number
- 59721-29-8
- Purity
- > 98%
- Form
- Solid
- Molecular weight
- 494.52 g/mol
- Molecular formula
- C20H22N4O5.CH4O3S
- Nature
- Synthetic
Recommended products
MW 494.52 g/mol, Purity >98%. Trypsin-like protease inhibitor. Reversibly inhibits airway epithelial sodium channel (ENaC) function (IC50 = 50 nM). Inhibits the production of TNF-α and monocyte chemoattractant protein-1 (MCP-1) by monocytes and disrupts proliferation of pancreatic stellate cells in a rat model of pancreatic fibrosis.
Inhibits transmembrane serine protease TMPRSS2 and blocks entry of SARS-Cov-2 into lung cells.
Key facts
- CAS number
- 59721-29-8
- Purity
- > 98%
- Form
- Solid
- Molecular weight
- 494.52 g/mol
- Molecular formula
- C20H22N4O5.CH4O3S
- Nature
- Synthetic
- Solubility
Soluble in water to 100 mM.
Soluble in DMSO to 100 mM.
- Biological description
Trypsin-like protease inhibitor. Reversibly inhibits airway epithelial sodium channel (ENaC) function (IC50 = 50 nM). Inhibits the production of TNF-α and monocyte chemoattractant protein-1 (MCP-1) by monocytes and disrupts proliferation of pancreatic stellate cells in a rat model of pancreatic fibrosis.
Inhibits transmembrane serine protease TMPRSS2 and blocks entry of SARS-Cov-2 into lung cells
- IUPAC name
- [4-[2-[2-(Dimethylamino)-2-oxoethoxy]-2-oxoethyl]phenyl] 4-(diaminomethylideneamino)benzoate methanesulfonate
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Store under desiccating conditions, The product can be stored for up to 12 months
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1 product image
Chemical Structure - Camostat mesylate, TMPRSS2 inhibitor (ab145709)
2D chemical structure image of ab145709, Camostat mesylate, TMPRSS2 inhibitor
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