Carboplatin, Antitumor agent

Key facts

CAS number

41575-94-4

Purity

>99%

Form

Solid

form

Molecular weight

371.25 Da

Molecular formula

C₆H₁₂N₂O₄Pt

PubChem

426756

Nature

Synthetic

Solubility

Trifluoroacetic Acid < 1 (mg/mL)

Soluble in water to 25 mM

Soluble in DMSO to 50 mM

Biochemical name

Carboplatin

Biological description

Antitumor agent. Forms platinum-DNA adducts blocking DNA replication and transcription. Displays lower nephrotoxicity than analog, cisplatin (ab141398). Active in vivo.

Canonical smiles

C1CC(C1)(C(=O)O)C(=O)O.[NH2-].[NH2-].[Pt+2]

InChi

InChI=1S/C6H8O4.2H2N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H2;/q;2*-1;+2

InChiKey

VSRXQHXAPYXROS-UHFFFAOYSA-N

IUPAC Name

azanide;cyclobutane-1,1-dicarboxylic acid;platinum(2+)