JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB145286

Carboxy-DCFDA N-succinimidyl ester, Fluorogenic esterase substrate

Be the first to review this product! Submit a review

|

(2 Publications)

MW 626.35 g/mol, Purity >96%. Cell-permeable, fluorogenic esterase substrate. Becomes hydrolyzed intracellularly to green fluorophore DCFA (ab145439) and covalently bonds to proteins.
1 Images
Chemical Structure - Carboxy-DCFDA N-succinimidyl ester, Fluorogenic esterase substrate (AB145286)
  • Chemical Structure

Lab

Chemical Structure - Carboxy-DCFDA N-succinimidyl ester, Fluorogenic esterase substrate (AB145286)

2D chemical structure image of ab145286, Carboxy-DCFDA N-succinimidyl ester, Fluorogenic esterase substrate

Key facts

CAS number

147265-60-9

Purity

>96%

Molecular weight

626.35 g/mol

Molecular formula

C<sub>2</sub><sub>9</sub>H<sub>1</sub><sub>7</sub>Cl<sub>2</sub>NO<sub>1</sub><sub>1</sub>

Nature

Synthetic

Solubility

Soluble in DMSO

Biological description

Cell-permeable, fluorogenic esterase substrate. Becomes hydrolyzed intracellularly to green fluorophore DCFA (ab145439) and covalently bonds to proteins.

InChi

InChI=1S/C25H16Cl2O6.C6H7NO4/c1-12(28)31-22-8-14-7-15-9-23(32-13(2)29)21(27)11-19(15)25(18(14)10-20(22)26)17-6-4-3-5-16(17)24(30)33-25;1-4(8)11-7-5(9)2-3-6(7)10/h3-6,8-11H,7H2,1-2H3;2-3H2,1H3

InChiKey

KPBFEPKORAGIIW-UHFFFAOYSA-N

IUPAC Name

5(6)-Carboxy-2',7'-dichlorofluorescein diacetate N-succinimidyl ester

Excitation/Emission

Ex: 495nm, Em: 529nm

style
left-column

Complementary Products

Biochemicals

AB145439

DCFA (5(6)-Carboxy-2',7'-dichlorofluorescein), green fluorophore

Chemical Structure - DCFA (5(6)-Carboxy-2',7'-dichlorofluorescein), green fluorophore (AB145439)

  • 0
  • 0
Assay Kits

AB113851

DCFDA / H2DCFDA - Cellular ROS Assay Kit

Cellular Activity - DCFDA / H2DCFDA - Cellular ROS Assay Kit (AB113851)

  • 5
  • 11
Biochemicals

AB145415

Carboxyl-DCFDA (5(6)-Carboxy-2',7'-dichlorofluorescein diacetate), Fluorogenic esterase substrate

Chemical Structure - Carboxyl-DCFDA (5(6)-Carboxy-2',7'-dichlorofluorescein diacetate), Fluorogenic esterase substrate (AB145415)

  • 0
  • 0
Assay Kits

AB186029

Cellular ROS Assay Kit (Deep Red)

Functional Studies - Cellular ROS Assay Kit (Deep Red) (AB186029)

  • 0
  • 0
style
left-column
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
style
left-column
style
left-column

Product protocols

style
left-column

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Environmental science and pollution research inter 24:21445-21458 PubMed28744684

2017

The chemistry and toxicity of discharge waters from copper mine tailing impoundment in the valley of the Apuseni Mountains in Romania.

Applications

Unspecified application

Species

Unspecified reactive species

Piotr Rzymski,Piotr Klimaszyk,Włodzimierz Marszelewski,Dariusz Borowiak,Mirosław Mleczek,Kamil Nowiński,Bożena Pius,Przemysław Niedzielski,Barbara Poniedziałek

Basic & clinical pharmacology & toxicology 116:96-109 PubMed25203460

2014

Cardioprotective and cardiotoxic effects of quercetin and two of its in vivo metabolites on differentiated h9c2 cardiomyocytes.

Applications

Unspecified application

Species

Unspecified reactive species

James Daubney,Philip L Bonner,Alan J Hargreaves,John M Dickenson
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com