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AB141911

Carmustine (BCNU), DNA alkylating agent

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(1 Publication)

MW 214.05 Da, Purity >99%. DNA alkylating agent. Forms interstrand crosslinks in DNA preventing DNA replication and transcription. Inhibitor of glutathione reductase, lipoamide dehydrogenase and trypanothione reductase. Active in vivo.
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Chemical Structure - Carmustine (BCNU), DNA alkylating agent (AB141911)
  • Chemical Structure

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Chemical Structure - Carmustine (BCNU), DNA alkylating agent (AB141911)

2D chemical structure image of ab141911, Carmustine (BCNU), DNA alkylating agent

Key facts

CAS number

154-93-8

Purity

>99%

Form

Solid

form

Molecular weight

214.05 Da

Molecular formula

C<sub>5</sub>H<sub>9</sub>Cl<sub>2</sub>N<sub>3</sub>O<sub>2</sub>

PubChem

2578

Nature

Synthetic

Solubility

Soluble in water to 25 mM

Soluble in ethanol to 100 mM

Soluble in DMSO to 100 mM

Biochemical name

Carmustine

Biological description

DNA alkylating agent. Forms interstrand crosslinks in DNA preventing DNA replication and transcription. Inhibitor of glutathione reductase, lipoamide dehydrogenase and trypanothione reductase. Active in vivo.

Canonical smiles

C(CCl)NC(=O)N(CCCl)N=O

InChi

InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)

InChiKey

DLGOEMSEDOSKAD-UHFFFAOYSA-N

IUPAC Name

1,3-bis(2-chloroethyl)-1-nitrosourea

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Biochemicals

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Secondary Antibodies

AB150113

Goat Anti-Mouse IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (AB150113)

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Primary Antibodies

AB18207

Anti-beta III Tubulin antibody - Neuronal Marker

BOND RX™ Validated|Lab Essentials|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-beta III Tubulin antibody - Neuronal Marker (AB18207)

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of cellular biochemistry 120:882-893 PubMed30216501

2018

FOXO1 associated with sensitivity to chemotherapy drugs and glial-mesenchymal transition in glioma.

Applications

Unspecified application

Species

Unspecified reactive species

Chao Chen,Guosheng Han,Yanan Li,Zhijian Yue,Laixing Wang,Jianmin Liu
View all publications
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