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AB142851

Castanospermine, alpha- and beta-glucosidase activity inhibitor

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MW 189.21 Da, Purity >98%. Potent sucrase (Ki =2.6 nM) and alpha and beta glucosidase activity inhibitor. Shows antiviral activity. Anti-inflammatory and immunosuppressive agent. Active in vivo and in vitro.

View Alternative Names

70 kDa lysosomal alpha-glucosidase, Acid Maltase, Acid alpha glucosidase, Aglucosidase Alfa, Alpha-glucosidase, Glucosidase alpha, Glucosidase alpha acid, Glucosidase alpha acid (Pompe disease glycogen storage disease type II), LYAG_HUMAN, Lysosomal Alpha-Glucosidase

1 Images
Chemical Structure - Castanospermine, alpha- and beta-glucosidase activity inhibitor (AB142851)
  • Chemical Structure

Lab

Chemical Structure - Castanospermine, alpha- and beta-glucosidase activity inhibitor (AB142851)

2D chemical structure image of ab142851, Castanospermine, alpha- and beta-glucosidase activity inhibitor

Key facts

CAS number

79831-76-8

Purity

>98%

Form

Solid

form

Source

Castanospermum australe

Molecular weight

189.21 Da

Molecular formula

C<sub>8</sub>H<sub>1</sub><sub>5</sub>NO<sub>4</sub>

PubChem

54445

Nature

Native

Solubility

Soluble in DMSO to 75 mM

Biochemical name

Castanospermine

Biological description

Potent sucrase (Ki =2.6 nM) and alpha and beta glucosidase activity inhibitor. Shows antiviral activity. Anti-inflammatory and immunosuppressive agent. Active in vivo and in vitro.

Canonical smiles

C1CN2CC(C(C(C2C1O)O)O)O

Isomeric smiles

C1CN2C[C@@H]([C@H]([C@@H]([C@H]2[C@H]1O)O)O)O

InChi

InChI=1S/C8H15NO4/c10-4-1-2-9-3-5(11)7(12)8(13)6(4)9/h4-8,10-13H,1-3H2/t4-,5-,6+,7+,8+/m0/s1

InChiKey

JDVVGAQPNNXQDW-TVNFTVLESA-N

IUPAC Name

(1S,6S,7R,8R,8aR)-1,2,3,5,6,7,8,8a-octahydroindolizine-1,6,7,8-tetrol

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 2293 Castanospermine. 2293-50 is the same size as the 50 mg size of ab142851.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months
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Product protocols

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