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AB120209

CCK Octapeptide sulfated, C-terminal ocatapeptide of CCK

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(2 Publications)

MW 1143.3 Da, Purity >97%. Achieve your results faster with highly validated, pure and trusted compounds.
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Functional Studies - CCK Octapeptide sulfated, C-terminal ocatapeptide of CCK (AB120209)
  • FuncS

Unknown

Functional Studies - CCK Octapeptide sulfated, C-terminal ocatapeptide of CCK (AB120209)

ab40794 staining FAK in PANC-1 cells treated with CCK Octapeptide sulfated (ab120209), by ICC/IF. Increase of FAK expression correlates with increased concentration of CCK Octapeptide sulfated, as described in literature.
The cells were incubated at 37°C for 10 minutes in media containing different concentrations of ab120209 (CCK Octapeptide sulfated) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab40794 (1/200) dilution was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight® 488 anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.

Chemical Structure - CCK Octapeptide sulfated, C-terminal ocatapeptide of CCK (AB120209)
  • Chemical Structure

Lab

Chemical Structure - CCK Octapeptide sulfated, C-terminal ocatapeptide of CCK (AB120209)

2D chemical structure image of ab120209, CCK Octapeptide sulfated, C-terminal ocatapeptide of CCK

Key facts

CAS number

25126-32-3

Purity

>97%

Form

Solid

form

Molecular weight

1143.3 Da

Molecular formula

C<sub>4</sub><sub>9</sub>H<sub>6</sub><sub>2</sub>N<sub>1</sub><sub>0</sub>O<sub>1</sub><sub>6</sub>S<sub>3</sub>

PubChem

32800

Nature

Synthetic

Solubility

Soluble in 0.1% NH4OH to 1mg/ml

Biochemical name

(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1-oxo-3-(4-sulfooxyphenyl)propan-2-yl]amino]-4-oxobutanoic acid

Canonical smiles

CSCCC(C(=O)NCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC3=CC=CC=C3)C(=O)N)NC(=O)C(CC4=CC=C(C=C4)OS(=O)(=O)O)NC(=O)C(CC(=O)O)N

InChi

InChI=1S/C49H62N10O16S3/c1-76-18-16-34(55-47(69)37(58-44(66)32(50)23-41(61)62)21-28-12-14-30(15-13-28)75-78(72,73)74)45(67)53-26-40(60)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(70)56-35(17-19-77-2)46(68)59-39(24-42(63)64)49(71)57-36(43(51)65)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52H,16-24,26,50H2,1-2H3,(H2,51,65)(H,53,67)(H,54,60)(H,55,69)(H,56,70)(H,57,71)(H,58,66)(H,59,68)(H,61,62)(H,63,64)(H,72,73,74)

InChiKey

IZTQOLKUZKXIRV-UHFFFAOYSA-N

IUPAC Name

3-amino-4-[[1-[[1-[[2-[[1-[[1-[[1-[(1-amino-1-oxo-3-phenylpropan-2-yl)amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1-oxo-3-(4-sulfooxyphenyl)propan-2-yl]amino]-4-oxobutanoic acid

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 46:297-304 PubMed32450570

2020

The vagus nerve mediates the suppressing effects of peripherally administered oxytocin on methamphetamine self-administration and seeking in rats.

Applications

Unspecified application

Species

Unspecified reactive species

Nicholas A Everett,Anita J Turner,Priscila A Costa,Sarah J Baracz,Jennifer L Cornish

The Journal of physiology 597:1487-1502 PubMed30565225

2018

Inducible nitric oxide synthase-derived nitric oxide reduces vagal satiety signalling in obese mice.

Applications

Unspecified application

Species

Unspecified reactive species

Yang Yu,Sung Jin Park,Michael J Beyak
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