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AB273533

CCT128930

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MW 341.8 Da, Purity 98%. Potent and selective AKT2 inhibitor (IC50= 6 nM) with selectivity greater than 28-fold and 20-fold over PKA kinase (IC50= 168 nM) and p70S6K (IC50= 120 nM), respectively.
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Chemical Structure - CCT128930 (AB273533)
  • Chemical Structure

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Chemical Structure - CCT128930 (AB273533)

Chemical structure of CCT128930, 885499-61-6

Key facts

CAS number

885499-61-6

Purity

98%

Form

Solid

form

Molecular weight

341.8 Da

Molecular formula

C<sub>1</sub><sub>8</sub>H<sub>2</sub><sub>0</sub>ClN<sub>5</sub>

PubChem

17751819

Nature

Synthetic

Solubility

Soluble in DMSO to 50 mM

Biochemical name

4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-amine

Biological description

Potent and selective AKT2 inhibitor (IC50= 6 nM) with selectivity greater than 28-fold and 20-fold over PKA kinase (IC50= 168 nM) and p70S6K (IC50= 120 nM), respectively.

Canonical smiles

C1CN(CCC1(CC2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4

InChi

InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23)

InChiKey

RZIDZIGAXXNODG-UHFFFAOYSA-N

IUPAC Name

4-[(4-chlorophenyl)methyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-amine

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Product details

For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while.
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
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Product protocols

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Biochemicals

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Biochemicals

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