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AB144218

Cercosporin, PKC inhibitor

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MW 534.5 Da, Purity >95%. Light-induced phytotoxin. Potent, selective competitive PKC inhibitor. Shows antiproliferative effects (IC50 = 4.68 μM, MCF7 cancer cell lines). Shows antimicrobial and antiparasitic effects in vivo. .
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Chemical Structure - Cercosporin, PKC inhibitor (AB144218)
  • Chemical Structure

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Chemical Structure - Cercosporin, PKC inhibitor (AB144218)

2D chemical structure image of ab144218, Cercosporin, PKC inhibitor

Key facts

CAS number

35082-49-6

Purity

>95%

Form

Solid

form

Source

Cercospora sp.

Molecular weight

534.5 Da

Molecular formula

C<sub>2</sub><sub>9</sub>H<sub>2</sub><sub>6</sub>O<sub>1</sub><sub>0</sub>

PubChem

2674

Nature

Native

Solubility

Soluble in ethanol

Soluble in DMSO

Biochemical name

Cercosporin from Cercospora hayii

Biological description

Light-induced phytotoxin. Potent, selective competitive PKC inhibitor. Shows antiproliferative effects (IC50 = 4.68 μM, MCF7 cancer cell lines). Shows antimicrobial and antiparasitic effects in vivo.

Canonical smiles

CC(CC1=C2C3=C(C(=C(C4=C3C5=C6C2=C(C(=O)C=C6OCOC5=CC4=O)C(=C1OC)O)O)OC)CC(C)O)O

InChi

InChI=1S/C29H26O10/c1-10(30)5-12-18-19-13(6-11(2)31)29(37-4)27(35)21-15(33)8-17-23(25(19)21)22-16(38-9-39-17)7-14(32)20(24(18)22)26(34)28(12)36-3/h7-8,10-11,30-31,34-35H,5-6,9H2,1-4H3

InChiKey

MXLWQNCWIIZUQT-UHFFFAOYSA-N

IUPAC Name

7,19-dihydroxy-5,21-bis(2-hydroxypropyl)-6,20-dimethoxy-12,14-dioxahexacyclo[13.8.0.02,11.03,8.04,22.018,23]tricosa-1,3(8),4,6,10,15,18(23),19,21-nonaene-9,17-dione

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Complementary Products

Biochemicals

AB219867

Sotrastaurin, pan-PKC inhibitor

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Primary Antibodies

AB195039

Anti-PKC beta 1 antibody [EPR18512]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PKC beta 1 antibody [EPR18512] (AB195039)

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Biochemicals

AB144414

Gouml 6983, PKC inhibitor

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Primary Antibodies

AB32376

Anti-PKC alpha antibody [Y124]

RabMAb|Recombinant|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-PKC alpha antibody [Y124] (AB32376)

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