JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB142047

Cerulenin, Fatty acid synthase inhibitor

Be the first to review this product! Submit a review

|

(0 Publication)

MW 223.27 Da, Purity >98%. Antifungal antibiotic. Fatty Acid Synthase (FAS) and steriod biosynthesis inhibitor. Binds covalently to the active center cysteine of the FAS condensing enzyme domain. Induces apoptosis in vivo.
1 Images
Chemical Structure - Cerulenin, Fatty acid synthase inhibitor (AB142047)
  • Chemical Structure

Lab

Chemical Structure - Cerulenin, Fatty acid synthase inhibitor (AB142047)

2D chemical structure image of ab142047, Cerulenin, Fatty acid synthase inhibitor

Key facts

CAS number

890090-50-3

Purity

>98%

Form

Solid

form

Molecular weight

223.27 Da

Molecular formula

C<sub>1</sub><sub>2</sub>H<sub>1</sub><sub>7</sub>NO<sub>3</sub>

PubChem

272023

Nature

Synthetic

Solubility

Soluble in DMSO to 75 mM

Soluble in ethanol to 75 mM

Biochemical name

2,3-Epoxy-4-oxo-7,10 dodecadienamide

Biological description

Antifungal antibiotic. Fatty Acid Synthase (FAS) and steriod biosynthesis inhibitor. Binds covalently to the active center cysteine of the FAS condensing enzyme domain. Induces apoptosis in vivo.

Canonical smiles

CC=CCC=CCCC(=O)C1C(O1)C(=O)N

InChi

InChI=1S/C12H17NO3/c1-2-3-4-5-6-7-8-9(14)10-11(16-10)12(13)15/h2-3,5-6,10-11H,4,7-8H2,1H3,(H2,13,15)

InChiKey

GVEZIHKRYBHEFX-UHFFFAOYSA-N

IUPAC Name

3-nona-4,7-dienoyloxirane-2-carboxamide

style
left-column

Complementary Products

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Biochemicals

AB141406

PDTC (Ammonium pyrrolidinedithiocarbamate), NF-kappaB inhibitor antioxidant

Chemical Structure - PDTC (Ammonium pyrrolidinedithiocarbamate), NF-kappaB inhibitor antioxidant (AB141406)

  • 0
  • 0
Biochemicals

AB143484

Cytochalasin D, actin polymerization inhibitor

Chemical Structure - Cytochalasin D, actin polymerization inhibitor (AB143484)

  • 0
  • 0
Biochemicals

AB144290

Latrunculin A (LAT-A), Actin polymerization inhibitor

Chemical Structure - Latrunculin A (LAT-A), Actin polymerization inhibitor (AB144290)

  • 0
  • 0
style
left-column

Product details

This product is manufactured by BioVision, an Abcam company and was previously called 1579 Cerulenin. 1579-50 is the same size as the 50 mg size of ab142047.
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

|

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

|

Refer to SDS for further information.

style
left-column
style
left-column
style
left-column

Product protocols

style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com