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AB120167

CGP 35348, GABAB antagonist

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(2 Publications)

MW 225.22 Da. Selective GABAB antagonist (IC50 = 34 μM). Brain penetrant *in vivo*. Also available in simple stock solutions (ab146707) - add 1 ml of water to get an exact, ready-to-use concentration.

View Alternative Names

BcDNA:GH07312, CG6706, CT20836, D Gaba2, FLJ36928, FLJ92613, G-protein coupled receptor 51, GAB B R2, GABA-B receptor 1, GABA-B receptor 2, GABA-B-R1, GABA-B-R2, GABAB subunit 1c, GABBR1, GABBR1 3, GABR1_HUMAN, GABR2_HUMAN, GH07312, GPR 51, GPRC 3B, GPRC3A, Gamma aminobutyric acid (GABA) B receptor 1, Gamma aminobutyric acid B receptor 2, Gamma aminobutyric acid GABA B receptor 2, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, Gb 2, Gb1, HG 20, HRIHFB2099, Metabotropic GABA B receptor subtype 2, OTTHUMP00000021776, OTTHUMP00000063797, R2 SUBUNIT, Seven transmembrane helix receptor, dJ271M21.1.1, dJ271M21.1.2

1 Images
Chemical Structure - CGP 35348, GABAB antagonist (AB120167)
  • Chemical Structure

Lab

Chemical Structure - CGP 35348, GABAB antagonist (AB120167)

2D chemical structure image of ab120167, CGP 35348, GABAB antagonist

Key facts

CAS number

123690-79-9

Form

Solid

form

Molecular weight

225.22 Da

Molecular formula

C<sub>8</sub>H<sub>2</sub><sub>0</sub>NO<sub>4</sub>P

PubChem

107699

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Biochemical name

3-Aminopropyl(diethoxymethyl)phosphinic acid

Biological description

Selective GABAB antagonist (IC50 = 34 μM). Brain penetrant *in vivo*. Also available in simple stock solutions (ab146707) - add 1 ml of water to get an exact, ready-to-use concentration.

Canonical smiles

CCOC(OCC)P(=O)(CCCN)O

InChi

InChI=1S/C8H20NO4P/c1-3-12-8(13-4-2)14(10,11)7-5-6-9/h8H,3-7,9H2,1-2H3,(H,10,11)

InChiKey

QIIVUOWTHWIXFO-UHFFFAOYSA-N

IUPAC Name

3-aminopropyl(diethoxymethyl)phosphinic acid

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Reproductive medicine and biology 22:e12528 PubMed37476368

2023

Gamma-aminobutyric acid (GABA) can affect physiological processes in preimplantation embryos via GABA and GABA receptors.

Applications

Unspecified application

Species

Unspecified reactive species

Veronika Kovaříková,Alexandra Špirková,Zuzana Šefčíková,Jozef Pisko,Laura Kalatová,Juraj Koppel,Dušan Fabian,Štefan Čikoš

Psychopharmacology 217:167-76 PubMed21484240

2011

GABA(B) receptor blockade in the hippocampus affects sensory and sensorimotor gating in Long-Evans rats.

Applications

Unspecified application

Species

Unspecified reactive species

Jingyi Ma,L Stan Leung
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