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MW 292.5 Da, Purity >98%. Positive GABAB receptor allosteric modulator (EC50 values are 5.37 and 4.60 μM, respectively). Increases receptor agonist affinity and signal transduction efficacy. Also shown to potentiate receptor response to baclofen (ab120325).

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Images

Chemical Structure - CGP 7930, Positive allosteric modulator of GABAB receptors (AB120492), expandable thumbnail

Key facts

CAS number
57717-80-3
Purity
> 98%
Form
Solid
Molecular weight
292.5 Da
Molecular formula
C19H32O2
PubChem identifier
5024764
Nature
Synthetic

Target data

Alternative names

1,8-cineole 2-exo-monooxygenase, AAD20, AI838772, AW493413, Albendazole monooxygenase, Albendazole sulfoxidase, Antigen NY-CO-13, BCC7, BcDNA:GH07312, CG6706, CP33, CP34, CP3A4_HUMAN, CPC12, CPC8, CPC9, CPCJ, CT20836, CYP2C, CYP2C10, CYP3, CYP3A, CYP3A3, CYP3A4, CYPIIIA3, CYPIIIA4, Cellular tumor antigen p53, Cytochrome P450 3A3, Cytochrome P450 3A4, Cytochrome P450 HLp, Cytochrome P450 NF-25, Cytochrome P450 family 3 subfamily A polypeptide 4, Cytochrome P450 subfamily IIIA polypeptide 4, Cytochrome P450-PCN1, D Gaba2, D(1A) dopamine receptor, D1A dopamine receptor, DADR, DKFZp686O15119, DRD 1A, DRD1_HUMAN, Dopamine D1 receptor, FLJ10358, FLJ11090, FLJ36928, FLJ92613, FLJ92943, G-protein coupled receptor 51, GAB B R2, GABA-B receptor 1, GABA-B receptor 2, GABA-B-R1, GABA-B-R2, GABAB subunit 1c, GABBR1, GABBR1 3, GABR1_HUMAN, GABR2_HUMAN, GAC, GAM, GH07312, GLP-1 receptor, GLP1R_HUMAN, GLS, GLS1, GLSK_HUMAN, GPR 51, GPRC 3B, GPRC3A, Gamma aminobutyric acid (GABA) B receptor 1, Gamma aminobutyric acid B receptor 2, Gamma aminobutyric acid GABA B receptor 2, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, Gb 2, Gb1, Glucagon-like peptide 1 receptor, Glucocorticoid inducible P450, Glutaminase C, Glutaminase kidney isoform, Glutaminase phosphate activated, HG 20, HLP, HRIHFB2099, K-glutaminase, KGA, KIAA0838, L-glutamine amidohydrolase, LFS1, MGC104252, MGC112732, MGC126680, MGC138331, Metabotropic GABA B receptor subtype 2, Mutant tumor protein 53, NF 25, Nifedipine oxidase, OTTHUMP00000016340, OTTHUMP00000021776, OTTHUMP00000063797, P450 III steroid inducible, P450 PB 1, P450 PCN1, P450, family III, P450C2C, P450C3, P450IIC19, P450IIC9, P53_HUMAN, Phosphoprotein p53, Quinine 3-monooxygenase, R2 SUBUNIT, RP24-311F12.2, SCAN1, Seven transmembrane helix receptor, TRP53, TYDP, TYDP1_HUMAN, Taurochenodeoxycholate 6-alpha-hydroxylase, Tp53, Transformation related protein 53, Tumor protein 53, Tumor protein p53, Tumor suppressor p53, Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4, dJ271M21.1.1, dJ271M21.1.2, dopamine receptor D1, mitochondrial, p53 tumor suppressor, tumor antigen p55

Recommended products

MW 292.5 Da, Purity >98%. Positive GABAB receptor allosteric modulator (EC50 values are 5.37 and 4.60 μM, respectively). Increases receptor agonist affinity and signal transduction efficacy. Also shown to potentiate receptor response to baclofen (ab120325).

Key facts

Purity
> 98%
PubChem identifier
5024764
Solubility

Soluble in DMSO to 100 mM.

Soluble in ethanol to 100 mM.

Biochemical name
2,6-Ditert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol
Biological description

Positive GABAB receptor allosteric modulator (EC50 values are 5.37 and 4.60 μM, respectively). Increases receptor agonist affinity and signal transduction efficacy. Also shown to potentiate receptor response to baclofen (ab120325).

Canonical SMILES
CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CC(C)(C)CO
InChI
InChI=1S/C19H32O2/c1-17(2,3)14-9-13(11-19(7,8)12-20)10-15(16(14)21)18(4,5)6/h9-10,20-21H,11-12H2,1-8H3
InChIKey
XLWJPQQFJNGUPA-UHFFFAOYSA-N
IUPAC name
2,6-ditert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

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1 product image

  • Chemical Structure - CGP 7930, Positive allosteric modulator of GABAB receptors (ab120492), expandable thumbnail

    Chemical Structure - CGP 7930, Positive allosteric modulator of GABAB receptors (ab120492)

    2D chemical structure image of ab120492, CGP 7930, Positive allosteric modulator of GABAB receptors

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