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AB120492

CGP 7930, Positive allosteric modulator of GABAB receptors

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MW 292.5 Da, Purity >98%. Positive GABAB receptor allosteric modulator (EC50 values are 5.37 and 4.60 μM, respectively). Increases receptor agonist affinity and signal transduction efficacy. Also shown to potentiate receptor response to baclofen (ab120325).
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Chemical Structure - CGP 7930, Positive allosteric modulator of GABAB receptors (AB120492)
  • Chemical Structure

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Chemical Structure - CGP 7930, Positive allosteric modulator of GABAB receptors (AB120492)

2D chemical structure image of ab120492, CGP 7930, Positive allosteric modulator of GABAB receptors

Key facts

CAS number

57717-80-3

Purity

>98%

Form

Solid

form

Molecular weight

292.5 Da

Molecular formula

C<sub>1</sub><sub>9</sub>H<sub>3</sub><sub>2</sub>O<sub>2</sub>

PubChem

5024764

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 100 mM

Biochemical name

2,6-Ditert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol

Biological description

Positive GABAB receptor allosteric modulator (EC50 values are 5.37 and 4.60 μM, respectively). Increases receptor agonist affinity and signal transduction efficacy. Also shown to potentiate receptor response to baclofen (ab120325).

Canonical smiles

CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CC(C)(C)CO

InChi

InChI=1S/C19H32O2/c1-17(2,3)14-9-13(11-19(7,8)12-20)10-15(16(14)21)18(4,5)6/h9-10,20-21H,11-12H2,1-8H3

InChiKey

XLWJPQQFJNGUPA-UHFFFAOYSA-N

IUPAC Name

2,6-ditert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol

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Biochemicals

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Primary Antibodies

AB192890

Anti-LC3B antibody [EPR18709] - Autophagosome Marker

BOND RX™ Validated|RabMAb|Recombinant|KO Validated|Lab Essentials|20ul selling size

Western blot - Anti-LC3B antibody [EPR18709] - Autophagosome Marker (AB192890)

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Product promise

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