JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB141622

Chaetomellic acid A, farnesyltransferase inhibitor

Be the first to review this product! Submit a review

|

(0 Publication)

MW 326.5 Da, Purity >98%. Potent, selective, competitive farnesyltransferase inhibitor (IC50 = 55 nM). Inhibits geranylgeranyltransferase I and II and protein prenyltransferase (IC50 values are 92, 34 and 17 μM respectively). Blocks Ha-Ras signalling. Active in vivo.
1 Images
Chemical Structure - Chaetomellic acid A, farnesyltransferase inhibitor (AB141622)
  • Chemical Structure

Lab

Chemical Structure - Chaetomellic acid A, farnesyltransferase inhibitor (AB141622)

2D chemical structure image of ab141622, Chaetomellic acid A, farnesyltransferase inhibitor

Key facts

CAS number

148796-51-4

Purity

>98%

Form

Solid

form

Molecular weight

326.5 Da

Molecular formula

C<sub>1</sub><sub>9</sub>H<sub>3</sub><sub>4</sub>O<sub>4</sub>

PubChem

3037595

Nature

Synthetic

Biochemical name

Chaetomellic acid A

Biological description

Potent, selective, competitive farnesyltransferase inhibitor (IC50 = 55 nM). Inhibits geranylgeranyltransferase I and II and protein prenyltransferase (IC50 values are 92, 34 and 17 μM respectively). Blocks Ha-Ras signalling. Active in vivo.

Canonical smiles

CCCCCCCCCCCCCCC(=C(C)C(=O)O)C(=O)O

Isomeric smiles

CCCCCCCCCCCCCC/C(=C(\C)/C(=O)O)/C(=O)O

InChi

InChI=1S/C19H34O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-17(19(22)23)16(2)18(20)21/h3-15H2,1-2H3,(H,20,21)(H,22,23)/b17-16-

InChiKey

ULSDRNDLXFVDED-MSUUIHNZSA-N

IUPAC Name

(Z)-2-methyl-3-tetradecylbut-2-enedioic acid

style
left-column

Complementary Products

Primary Antibodies

AB109738

Anti-FNTA antibody [EPR4704]

RabMAb|Recombinant

Western blot - Anti-FNTA antibody [EPR4704] (AB109738)

  • 0
  • 0
style
left-column
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
style
left-column
style
left-column
style
left-column

Product protocols

style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com