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AB146008

CHC, Monocarboxylic acid transport inhibitor

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(1 Publication)

MW 189.17 g/mol, Purity >98%. Monocarboxylic acid transport (MCT) inhibitor. Exhibits antitumoral and antiangiogenic activity in gliomas in vivo. Decreases glycolytic metabolism, migration, and invasion in U251 cells. Enhances the effect of the DNA-methylating antitumor agent temozolomide (ab141055).
1 Images
Chemical Structure - CHC, Monocarboxylic acid transport inhibitor (AB146008)
  • Chemical Structure

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Chemical Structure - CHC, Monocarboxylic acid transport inhibitor (AB146008)

2D chemical structure image of ab146008, CHC, Monocarboxylic acid transport inhibitor

Key facts

CAS number

28166-41-8

Purity

>98%

Form

Solid

form

Molecular weight

189.17 g/mol

Molecular formula

C<sub>1</sub><sub>0</sub>H<sub>7</sub>NO<sub>3</sub>

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 50 mM

Biological description

Monocarboxylic acid transport (MCT) inhibitor. Exhibits antitumoral and antiangiogenic activity in gliomas in vivo. Decreases glycolytic metabolism, migration, and invasion in U251 cells. Enhances the effect of the DNA-methylating antitumor agent temozolomide (ab141055).

IUPAC Name

2-Cyano-3-(4-hydroxyphenyl)-2-propenoic acid

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months

Product protocols

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Toxicology in vitro : an international journal pub 59:246-254 PubMed31009676

2019

Fibroblast growth factor 21 secretion enhances glucose uptake in mono(2-ethylhexyl)phthalate-treated adipocytes.

Applications

Unspecified application

Species

Unspecified reactive species

Jhih-Wei Hsu,Szu-Ching Yeh,Feng-Yuan Tsai,Hsin-Wei Chen,Tsui-Chun Tsou
View all publications

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