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MW 515.9 Da, Purity >98%. Antimalarial agent. Inhibits tumor cell growth and metastasis and induces apoptosis in vitro. Binds to Fe(II)-protoporphyrin IX (FP) to form FP-chloroquine complex resulting in cell lysis and parasite cell autodigestion.
Alternative names=ACEE, ACES_HUMAN, ACLS, AIS, ANDR_HUMAN, AR, AR8, ARACHE, Acetylcholinesterase, Androgen nuclear receptor variant 2, Androgen receptor, Androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease), Apoptosis related acetylcholinesterase, CAR, CAR BETA, CARA, Car 1, Constitutive activator of retinoid response, Constitutive active response, Constitutive androstane receptor, DHTR, DNA binding protein, Dihydro testosterone receptor, Dihydrotestosterone receptor (DHTR), GCPS, GLI Kruppel family member GLI 3, GLI Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome), GLI family zinc finger 3, GLI3 C-terminally truncated form, GLI3 form of 190 kDa, GLI3 form of 83 kDa, GLI3 full length protein, GLI3-190, GLI3-83, GLI3FL, GLI3_HUMAN, Glioma associated oncogene family zinc finger 3, HUMARA, HYSP1, KD, Kennedy disease (KD), MB67, MGC97144, N-ACHE, NR1I3_HUMAN, NR3C3, NR3C4, Nuclear receptor subfamily 1 group I member 3, Nuclear receptor subfamily 3 group C member 3, Nuclear receptor subfamily 3 group C member 4, Nuclear receptor subfamily 3 group C member 4 (NR3C4), Oncogene GLI3, Orphan nuclear receptor MB67, Orphan nuclear receptor NR1I3, PAP A, PAPB, PGR, PPD IV, PR, PRA, PRB, PRGR_HUMAN, Progesterone receptor, Progestin receptor form A, Progestin receptor form B, SBMA, SMAX1, Spinal and bulbar muscular atrophy, Spinal and bulbar muscular atrophy (SBMA), TFM, Testicular Feminization (TFM), Transcriptional activator GLI3, Transcriptional repressor GLI3R, YT, YT blood group, Zinc finger protein GLI 3, androgen receptor splice variant 4b, constitutive active receptor, constitutive androstane nuclear receptor variant 2, constitutive androstane nuclear receptor variant 3, constitutive androstane nuclear receptor variant 4, constitutive androstane nuclear receptor variant 5, orphan nuclear hormone receptor
- CAS number
50-63-5
- Purity
> 98%
- Form
Solid
- Molecular weight
515.9 Da
- Molecular formula
C18H32ClN3O8P2
- PubChem identifier
64927
- Nature
Synthetic
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MW 515.9 Da, Purity >98%. Antimalarial agent. Inhibits tumor cell growth and metastasis and induces apoptosis in vitro. Binds to Fe(II)-protoporphyrin IX (FP) to form FP-chloroquine complex resulting in cell lysis and parasite cell autodigestion.
Alternative names=ACEE, ACES_HUMAN, ACLS, AIS, ANDR_HUMAN, AR, AR8, ARACHE, Acetylcholinesterase, Androgen nuclear receptor variant 2, Androgen receptor, Androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease), Apoptosis related acetylcholinesterase, CAR, CAR BETA, CARA, Car 1, Constitutive activator of retinoid response, Constitutive active response, Constitutive androstane receptor, DHTR, DNA binding protein, Dihydro testosterone receptor, Dihydrotestosterone receptor (DHTR), GCPS, GLI Kruppel family member GLI 3, GLI Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome), GLI family zinc finger 3, GLI3 C-terminally truncated form, GLI3 form of 190 kDa, GLI3 form of 83 kDa, GLI3 full length protein, GLI3-190, GLI3-83, GLI3FL, GLI3_HUMAN, Glioma associated oncogene family zinc finger 3, HUMARA, HYSP1, KD, Kennedy disease (KD), MB67, MGC97144, N-ACHE, NR1I3_HUMAN, NR3C3, NR3C4, Nuclear receptor subfamily 1 group I member 3, Nuclear receptor subfamily 3 group C member 3, Nuclear receptor subfamily 3 group C member 4, Nuclear receptor subfamily 3 group C member 4 (NR3C4), Oncogene GLI3, Orphan nuclear receptor MB67, Orphan nuclear receptor NR1I3, PAP A, PAPB, PGR, PPD IV, PR, PRA, PRB, PRGR_HUMAN, Progesterone receptor, Progestin receptor form A, Progestin receptor form B, SBMA, SMAX1, Spinal and bulbar muscular atrophy, Spinal and bulbar muscular atrophy (SBMA), TFM, Testicular Feminization (TFM), Transcriptional activator GLI3, Transcriptional repressor GLI3R, YT, YT blood group, Zinc finger protein GLI 3, androgen receptor splice variant 4b, constitutive active receptor, constitutive androstane nuclear receptor variant 2, constitutive androstane nuclear receptor variant 3, constitutive androstane nuclear receptor variant 4, constitutive androstane nuclear receptor variant 5, orphan nuclear hormone receptor
Key facts
- CAS number
50-63-5
- Purity
> 98%
- Form
Solid
- Molecular weight
515.9 Da
- Molecular formula
C18H32ClN3O8P2
- PubChem identifier
64927
- Nature
Synthetic
- Biochemical name
Chloroquine phosphate
- Biological description
Antimalarial agent. Inhibits tumor cell growth and metastasis and induces apoptosis in vitro. Binds to Fe(II)-protoporphyrin IX (FP) to form FP-chloroquine complex resulting in cell lysis and parasite cell autodigestion.
- Canonical SMILES
CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl.OP(=O)(O)O.OP(=O)(O)O
- InChI
InChI=1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4)
- InChIKey
QKICWELGRMTQCR-UHFFFAOYSA-N
- IUPAC name
4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine;phosphoric acid
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
-20°C
- Storage information
Store under desiccating conditions, The product can be stored for up to 12 months
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