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AB143476

Citrinin, tubulin polymerization inhibitor

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MW 250.25 Da, Purity >98%. Mycotoxin. Tubulin polymerization inhibitor. Prevents mitotic spindle formation. Induces cell cycle arrest at G2/M phase and apoptosis. Shows nephrotoxic effects in vivo. Orally active.
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Chemical Structure - Citrinin, tubulin polymerization inhibitor (AB143476)
  • Chemical Structure

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Chemical Structure - Citrinin, tubulin polymerization inhibitor (AB143476)

2D chemical structure image of ab143476, Citrinin, tubulin polymerization inhibitor

Key facts

CAS number

11118-72-2

Purity

>98%

Form

Solid

form

Source

Penicillium citrinum

Molecular weight

250.25 Da

Molecular formula

C<sub>1</sub><sub>3</sub>H<sub>1</sub><sub>4</sub>O<sub>5</sub>

PubChem

54682830

Nature

Native

Biochemical name

8-Hydroxy-3,4,5-trimethyl-6-oxo-4,6-dihydro-3H-isochromene-7-carboxylic acid

Biological description

Mycotoxin. Tubulin polymerization inhibitor. Prevents mitotic spindle formation. Induces cell cycle arrest at G2/M phase and apoptosis. Shows nephrotoxic effects in vivo. Orally active.

Canonical smiles

CC1C(OC=C2C1=C(C(=C(C2=O)C(=O)O)O)C)C

InChi

InChI=1S/C13H14O5/c1-5-7(3)18-4-8-9(5)6(2)11(14)10(12(8)15)13(16)17/h4-5,7,14H,1-3H3,(H,16,17)

InChiKey

CBGDIJWINPWWJW-UHFFFAOYSA-N

IUPAC Name

6-hydroxy-3,4,5-trimethyl-8-oxo-3,4-dihydroisochromene-7-carboxylic acid

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months
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Product protocols

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