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MW 276.12 Da, Purity >99%. Water soluble, potent, competitive AMPA / kainate receptor antagonist. Also antagonist at NMDA receptor glycine site.

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Images

Chemical Structure - CNQX disodium salt (mM/ml), AMPA / kainate antagonist (water soluble) (AB144488), expandable thumbnail
  • Flow Cytometry - CNQX disodium salt (mM/ml), AMPA / kainate antagonist (water soluble) (AB144488), expandable thumbnail

Publications

Key facts

Purity

> 99%

Form

Solid

Molecular weight

276.12 Da

Molecular formula

C9H2N4Na2O4

PubChem identifier

2821

Nature

Synthetic

Alternative names

Recommended products

MW 276.12 Da, Purity >99%. Water soluble, potent, competitive AMPA / kainate receptor antagonist. Also antagonist at NMDA receptor glycine site.

Key facts

Purity

> 99%

PubChem identifier

2821

Solubility

Soluble in 1 ml of water to give specified mM/ml concentration.

Biochemical name

CNQX disodium

Biological description

Water soluble, potent, competitive AMPA / kainate receptor antagonist. Also antagonist at NMDA receptor glycine site.

Canonical SMILES

C1=C(C(=CC2=C1N=C(C(=N2)[O-])[O-])[N+](=O)[O-])C#N.[Na+].[Na+]

InChI

InChI=1S/C9H4N4O4.2Na/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5;;/h1-2H,(H,11,14)(H,12,15);;/q;2*+1/p-2

InChIKey

YCXDDPGRZKUGDG-UHFFFAOYSA-L

IUPAC name

disodium;6-cyano-7-nitroquinoxaline-2,3-diolate

Storage

Shipped at conditions

Ambient - Can Ship with Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

Storage information

Store under desiccating conditions, The product can be stored for up to 12 months

Product promise

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2 product images

  • Chemical Structure - CNQX disodium salt (mM/ml), AMPA / kainate antagonist (water soluble) (ab144488), expandable thumbnail

    Chemical Structure - CNQX disodium salt (mM/ml), AMPA / kainate antagonist (water soluble) (ab144488)

    2D chemical structure image of ab144488, CNQX disodium salt (mM/ml), AMPA / kainate antagonist (water soluble)

  • Flow Cytometry - CNQX disodium salt (mM/ml), AMPA / kainate antagonist (water soluble) (ab144488), expandable thumbnail
    Kellett et al PLoS One. 2010; 5(7): e11737. Reproduced under the Creative Commons license http://creativecommons.org/licenses/by/4.0/

    Flow Cytometry - CNQX disodium salt (mM/ml), AMPA / kainate antagonist (water soluble) (ab144488)

    Effects of cortical and nuclear CNQX on performance of established CRs.

    Mean (±1 SEM) effects of CNQX (6 nmol) on CR performance when infused into cortical (2 μl; top panels) or nuclear cannulae (1 μl; bottom panels).

    (From Figure 4 of Kellett et al).

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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