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AB141429

CP 154526 hydrochloride, non-peptide CRF1 receptor antagonist

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MW 400.99 g/mol, Purity >99%. Potent, selective, non-peptide corticotropin factor receptor-1 antagonist (Ki = 10 nM). Blood-brain barrier permeable. Neuroprotective and antistress agent. Active in vivo and in vitro.
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Chemical Structure - CP 154526 hydrochloride, non-peptide CRF1 receptor antagonist (AB141429)
  • Chemical Structure

Lab

Chemical Structure - CP 154526 hydrochloride, non-peptide CRF1 receptor antagonist (AB141429)

2D chemical structure image of ab141429, CP 154526 hydrochloride, non-peptide CRF1 receptor antagonist

Key facts

CAS number

257639-98-8

Purity

>99%

Form

Solid

form

Molecular weight

400.99 g/mol

Molecular formula

C<sub>2</sub><sub>3</sub>H<sub>3</sub><sub>2</sub>N<sub>4</sub>.HCl

Nature

Synthetic

Solubility

Soluble in ethanol to 50 mM

Soluble in DMSO to 50 mM

Biological description

Potent, selective, non-peptide corticotropin factor receptor-1 antagonist (Ki = 10 nM). Blood-brain barrier permeable. Neuroprotective and antistress agent. Active in vivo and in vitro.

Canonical smiles

CL.CCN(CCCC)C1NC(C)NC2C1C(C)CN2C3C(C)CC(C)CC3C

InChi

InChI=1S/C23H32N4.ClH/c1-8-10-11-26(9-2)22-20-18(6)14-27(23(20)25-19(7)24-22)21-16(4)12-15(3)13-17(21)5;/h12-14H,8-11H2,1-7H3;1H

InChiKey

ZWDLBNCJWNENFF-UHFFFAOYSA-N

IUPAC Name

N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine hydrochloride

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Complementary Products

Secondary Antibodies

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Biochemicals

AB141002

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Primary Antibodies

AB13847

Anti-Caspase-3 antibody

KO Validated

Western blot - Anti-Caspase-3 antibody (AB13847)

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Primary Antibodies

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Western blot - Anti-c-Fos antibody [EPR883(2)] (AB134122)

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