JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB141018

Cypermethrin, Neurotoxin

Be the first to review this product! Submit a review

|

(0 Publication)

MW 416.3 Da, Purity >98%. Synthetic pyrethroid. Interacts with sodium channels inducing cellular hyperexcitability leading to neurotoxicity. Additionally inhibits calcineurin. Active in vivo. Blood-brain barrier permeable.

View Alternative Names

AHDC, ALDC, ALDH 1, ALDH 11, ALDH class 1, ALDH class 2, ALDH-E1, ALDH-E2, ALDHI, ALDM, ALHDII, Acetaldehyde dehydrogenase 1, Acetaldehyde dehydrogenase 2, Aldehyde dehydrogenase 1, Aldehyde dehydrogenase 1 family member A1, Aldehyde dehydrogenase 1 soluble, Aldehyde dehydrogenase 1A1, Aldehyde dehydrogenase 2 family, Aldehyde dehydrogenase 2 family (mitochondrial), Aldehyde dehydrogenase cytosolic, Aldehyde dehydrogenase liver cytosolic, Aldehyde dehydrogenase mitochondrial, Aldh, BXR, ERR a, ERR-alpha, ERR1 protein, ERR1_HUMAN, ESRL 1, ESRR A, Estrogen receptor related 1, Estrogen receptor-like 1, Estrogen-related receptor alpha, Estrra, Liver mitochondrial ALDH, MGC1806, MGC2318, Mitochondrial aldehyde dehydrogenase 2, NR1I2_HUMAN, NR3B1, Nuclear receptor subfamily 1 group I member 2, Nuclear receptor subfamily 3 group B member 1, Nucleus encoded mitochondrial aldehyde dehydrogenase 2, ONR 1, OTTHUMP00000215173, OTTHUMP00000215174, OTTHUMP00000215175, Orphan nuclear receptor PAR 1, Orphan nuclear receptor PXR, PAR, PAR q, PRR, PUMB 1, Pregnane X receptor, RALDH 1, Retinal dehydrogenase 1, Retinaldehyde dehydrogenase 1, SXR, Steroid and xenobiotic receptor, Steroid hormone receptor ERR1, estrogen receptor related receptor alpha, hERR1, pregnane X nuclear receptor variant 2

1 Images
Chemical Structure - Cypermethrin, Neurotoxin (AB141018)
  • Chemical Structure

Lab

Chemical Structure - Cypermethrin, Neurotoxin (AB141018)

2D chemical structure image of ab141018, Cypermethrin, Neurotoxin

Key facts

CAS number

52315-07-8

Purity

>98%

Form

Solid

form

Molecular weight

416.3 Da

Molecular formula

C<sub>2</sub><sub>2</sub>H<sub>1</sub><sub>9</sub>Cl<sub>2</sub>NO<sub>3</sub>

PubChem

2912

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 50 mM

Biochemical name

Cypermethrin

Biological description

Synthetic pyrethroid. Interacts with sodium channels inducing cellular hyperexcitability leading to neurotoxicity. Additionally inhibits calcineurin. Active in vivo. Blood-brain barrier permeable.

Canonical smiles

CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C

InChi

InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3

InChiKey

KAATUXNTWXVJKI-UHFFFAOYSA-N

IUPAC Name

[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com