MW 243.22 Da, Purity >99%. Pyrimidine nucleoside analog able to inhibits DNA synthesis. Active specifically on the S phase of the cell cycle. Chemotherapeutic agent. Antiviral and immunosuppressant properties.
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- Frontiers in cellular neuroscience 12:442018An Easy-to-Implement Protocol for Preparing Postnatal Ventral Mesencephalic Cultures.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJanin Lautenschläger et. al.PubMed 29556177
- Journal of biomedical nanotechnology 8:928-372012Synthesis of cytarabine lipid drug conjugate for treatment of meningeal leukemia: development, characterization and in vitro cell line studies.Applications:Unspecified applicationReactive species:Unspecified reactive speciesPravin Sharma,Brahmanand Dube,Krutika SawantPubMed 23030001
- Blood 107:2517-242005Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial.Applications:Unspecified applicationReactive species:Unspecified reactive speciesDeepa Sampath,Jorge Cortes,Zeev Estrov,Min Du,Zheng Shi,Michael Andreeff,Varsha Gandhi,William PlunkettPubMed 16293603
- Clinical pharmacokinetics 41:705-182002Clinical pharmacokinetics of cytarabine formulations.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAkinobu Hamada,Takeo Kawaguchi,Masahiro NakanoPubMed 12162758
Key facts
- CAS number
147-94-4
- Purity
> 99%
- Form
Solid
- Molecular weight
243.22 Da
- Molecular formula
C9H13N3O5
- PubChem identifier
6253
- Nature
Synthetic
Target data
Alternative names
ACTR, AI838772, AIB-1, AIS, ANDR_HUMAN, AR, AR8, AW493413, Amplified in breast cancer 1, Amplified in breast cancer 1 protein, Androgen nuclear receptor variant 2, Androgen receptor, Androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease), Antigen NY-CO-13, BCC7, CAGH 16, CAR, CAR BETA, CARA, CBP-interacting protein, CTG 26, Car 1, Cellular tumor antigen p53, Class E basic helix-loop-helix protein 42, Constitutive activator of retinoid response, Constitutive active response, Constitutive androstane receptor, DHTR, Dihydro testosterone receptor, Dihydrotestosterone receptor (DHTR), EC 2.1.1.45, FLJ11090, FLJ92943, HUMARA, HYSP1, HsT422, IMD42, KAT13B / AIB1, KD, Kennedy disease (KD), LFS1, MB67, MGC104252, MGC112732, MGC129539, MGC141848, MGC88736, MGC97144, Mutant tumor protein 53, NCOA3_HUMAN, NR1F3, NR1I3_HUMAN, NR3C4, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor coactivator 3, Nuclear receptor subfamily 1 group F member 3, Nuclear receptor subfamily 1 group I member 3, Nuclear receptor subfamily 3 group C member 4, Nuclear receptor subfamily 3 group C member 4 (NR3C4), OTTHUMP00000162195, Orphan nuclear receptor MB67, Orphan nuclear receptor NR1I3, P53_HUMAN, Phosphoprotein p53, RAR related orphan nuclear receptor variant 2, RAR related orphan receptor C, isoform a, RAR related orphan receptor gamma, RAR-related orphan receptor C, RORG_HUMAN, RP24-311F12.2, RZR GAMMA, RZRG, Receptor-associated coactivator 3, Retinoic acid binding receptor gamma, Retinoid-related orphan receptor-gamma, Rorc, SBMA, SCAN1, SMAX1, Spinal and bulbar muscular atrophy, Spinal and bulbar muscular atrophy (SBMA), Steroid receptor coactivator protein 3, TFM, TMS, TNRC 14, TNRC16, TOR, TRP53, TS, TSase, TYDP, TYDP1_HUMAN, TYMS protein, TYSY_HUMAN, Testicular Feminization (TFM), Thymidylate synthase, Thymidylate synthetase, Thyroid hormone receptor activator molecule 1, Tp53, Transformation related protein 53, Tumor protein 53, Tumor protein p53, Tumor suppressor p53, Tyms, Tyms thymidylate synthetase, Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1, androgen receptor splice variant 4b, bHLHe42, constitutive active receptor, constitutive androstane nuclear receptor variant 2, constitutive androstane nuclear receptor variant 3, constitutive androstane nuclear receptor variant 4, constitutive androstane nuclear receptor variant 5, d TMP synthase, orphan nuclear hormone receptor, p53 tumor suppressor, pCIP, tumor antigen p55
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MW 243.22 Da, Purity >99%. Pyrimidine nucleoside analog able to inhibits DNA synthesis. Active specifically on the S phase of the cell cycle. Chemotherapeutic agent. Antiviral and immunosuppressant properties.
Key facts
- CAS number
147-94-4
- Purity
> 99%
- Form
Solid
- Molecular weight
243.22 Da
- Molecular formula
C9H13N3O5
- PubChem identifier
6253
- Nature
Synthetic
- Solubility
1 G IN ABOUT 5 ML WATER & 500 ML ALC; 1 G IN ABOUT 1000 ML CHLOROFORM & 300 ML METHANOL. In water, 1X10+6 mg/L at 25 °C (miscible) (est).
- Biochemical name
Cytarabine
- Biological description
Pyrimidine nucleoside analog able to inhibits DNA synthesis. Active specifically on the S phase of the cell cycle. Chemotherapeutic agent. Antiviral and immunosuppressant properties.
- Canonical SMILES
C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O
- Isomeric SMILES
C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O
- InChI
InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1
- InChIKey
UHDGCWIWMRVCDJ-CCXZUQQUSA-N
- IUPAC name
4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
Ambient
- Appropriate long-term storage conditions
Ambient
- Storage information
The product can be stored for up to 12 months
Product promise
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Chemical Structure - Cytarabine, Pyrimidine nucleoside analog (ab141924)
2D chemical structure image of ab141924, Cytarabine, Pyrimidine nucleoside analog
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