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AB120537

(-)-Cytisine, neuronal nicotinic agonist

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(1 Publication)

MW 190.24 Da, Purity >99%. Potent, selective agonist at neuronal nicotinic receptors. Acts as a partial agonist at β2-containing nicotinic receptors. (Ki values are 2 (α4β2), 5890 (α7), 480 (α3β4), 329 (α6/α4β4) and 492 nM (α1β1γδ)).
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Chemical Structure - (-)-Cytisine, neuronal nicotinic agonist (AB120537)
  • Chemical Structure

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Chemical Structure - (-)-Cytisine, neuronal nicotinic agonist (AB120537)

2D chemical structure image of ab120537, (-)-Cytisine, neuronal nicotinic agonist

Key facts

CAS number

15191-27-2

Purity

>99%

Form

Solid

form

Molecular weight

190.24 Da

Molecular formula

C<sub>1</sub><sub>1</sub>H<sub>1</sub><sub>4</sub>N<sub>2</sub>O

PubChem

22407

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Biochemical name

(-)-Cytisine

Biological description

Potent, selective agonist at neuronal nicotinic receptors. Acts as a partial agonist at β2-containing nicotinic receptors. (Ki values are 2 (α4β2), 5890 (α7), 480 (α3β4), 329 (α6/α4β4) and 492 nM (α1β1γδ)).

Canonical smiles

C1C2CNCC1C3=CC=CC(=O)N3C2

InChi

InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2

InChiKey

ANJTVLIZGCUXLD-UHFFFAOYSA-N

IUPAC Name

7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

The Journal of physiology 591:203-17 PubMed23045343

2012

Direct and GABA-mediated indirect effects of nicotinic ACh receptor agonists on striatal neurones.

Applications

Unspecified application

Species

Unspecified reactive species

Ruixi Luo,Megan J Janssen,John G Partridge,Stefano Vicini
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