AB143484

Cytochalasin D, actin polymerization inhibitor

Name: Cytochalasin D, actin polymerization inhibitor (CAS 22144-77-0) | Abcam
Brand: Abcam Limited
SKU: AB143484
Price: 240 USD
Availability: InStock

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(24 Publications)

MW 507.6 Da, Purity >98%. Achieve your results faster with highly validated, pure and trusted compounds.

1 Images

Chemical Structure - Cytochalasin D, actin polymerization inhibitor (AB143484)

Chemical Structure

Lab

Chemical Structure - Cytochalasin D, actin polymerization inhibitor (AB143484)

2D chemical structure image of ab143484, Cytochalasin D, actin polymerization inhibitor

Key facts

CAS number

22144-77-0

Purity

>98%

Form

Solid

form

Source

Zygosporium mansonii

Molecular weight

507.6 Da

Molecular formula

C30H37NO6

PubChem

5458428

Nature

Native

Biochemical name

cytochalasin D

Canonical smiles

CC1CC=CC2C(C(=C)C(C3C2(C(C=CC(C1=O)(C)O)OC(=O)C)C(=O)NC3CC4=CC=CC=C4)C)O

Isomeric smiles

C[C@H]1C/C=C/[C@H]2[C@@H](C(=C)[C@H]([C@@H]3[C@@]2([C@@H](/C=C/[C@@](C1=O)(C)O)OC(=O)C)C(=O)N[C@H]3CC4=CC=CC=C4)C)O

InChi

InChI=1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17-18,22-26,33,36H,3,10,16H2,1-2,4-5H3,(H,31,35)/b13-9+,15-14+/t17-,18+,22-,23-,24+,25-,26+,29+,30+/m0/s1

InChiKey

SDZRWUKZFQQKKV-JHADDHBZSA-N

IUPAC Name

[(1R,2R,3E,5R,7S,9E,11R,12S,14S,15R,16S)-16-benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-6,18-dioxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl] acetate

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Properties and storage information

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

-20°C

Appropriate long-term storage conditions

-20°C

Storage information

Store under desiccating conditions|The product can be stored for up to 12 months

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Product protocols

Visit the General protocols
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Publications (24)

Recent publications for all applications. Explore the full list and refine your search

ImmunoHorizons 9: PubMed40288813

2025

PTEN inhibits scavenger receptor-mediated phagocytosis of methicillin-resistant Staphylococcus aureus.

Applications

Unspecified application

Species

Unspecified reactive species

Eden E Faneuff,Min Joo Kim,Amondrea Blackman,Kirti A Karunakaran,Jackie E Bader,Xin Zhen,Kaitlyn S Gallagher,Tanner J Durst,James A Connelly,Jeffrey C Rathmell,Ana Salina,Ruben Martinez-Barricarte,Carlos Henrique Serezani

Communications biology 8:607 PubMed40229503

2025

Primary cilia prevent activation of the cGAS-STING pathway during mouse decidualization.

Applications

Unspecified application

Species

Unspecified reactive species

Bo Li,Yu-Ying He,Wen-Xu Yao,Dan-Dan Jin,Hui-Na Luo,Meng-Yuan Li,Ying Wu,Zeng-Ming Yang

Cellular and molecular life sciences : CMLS 82:114 PubMed40074991

2025

Neutrophil-modulated Dicer expression in macrophages influences inflammation resolution.

Applications

Unspecified application

Species

Unspecified reactive species

Zhishang Wang,Wenhua Li,Jia Li,Tianrong Jin,Hong Chen,Feihong Liang,Shengran Liu,Jialin Jia,Tingting Liu,Yu Liu,Liming Yu,Xiaodong Xue,Jikai Zhao,Tao Huang,Xinyi Huang,Huishan Wang,Yongsheng Li,Bangwei Luo,Zhiren Zhang

Nature communications 15:10476 PubMed39668169

2024

An actin bracket-induced elastoplastic transition determines epithelial folding irreversibility.

Applications

Unspecified application

Species

Unspecified reactive species

Aki Teranishi,Misato Mori,Rihoko Ichiki,Satoshi Toda,Go Shioi,Satoru Okuda

Nature protocols 20:336-362 PubMed39215132

2024

A bioswitchable delivery system for microRNA therapeutics based on a tetrahedral DNA nanostructure.

Applications

Unspecified application

Species

Unspecified reactive species

Songhang Li,Taoran Tian,Tao Zhang,Yunfeng Lin,Xiaoxiao Cai

Molecular biology of the cell 35:ar64 PubMed38507235

2024

CD56/NCAM mediates cell migration of human NK cells by promoting integrin-mediated adhesion turnover.

Applications

Unspecified application

Species

Unspecified reactive species

Amera L Martinez,Michael J Shannon,Tyler Sloan,Emily M Mace

Journal of neurochemistry 168:100-114 PubMed38102893

2023

Mechanisms of aquaporin-4 vesicular trafficking in mammalian cells.

Applications

Unspecified application

Species

Unspecified reactive species

Andrea Markou,Philip Kitchen,Ahmed Aldabbagh,Mariaelena Repici,Mootaz M Salman,Roslyn M Bill,Zita Balklava

Journal of virology 97:e0077023 PubMed37823645

2023

Efficient clathrin-mediated entry of enteric adenoviruses in human duodenal cells.

Applications

Unspecified application

Species

Unspecified reactive species

Miriam Becker,Dario Valter Conca,Noemi Dorma,Nitesh Mistry,Elin Hahlin,Lars Frängsmyr,Marta Bally,Niklas Arnberg,Gisa Gerold

FEMS microbes 4:xtad019 PubMed37900578

2023

suppresses -induced NETosis and promotes bacterial survival in polymicrobial infections.

Applications

Unspecified application

Species

Unspecified reactive species

Patrick Hsien-Neng Kao,Jun-Hong Ch'ng,Kelvin K L Chong,Claudia J Stocks,Siu Ling Wong,Kimberly A Kline

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 9:e2105365 PubMed35619548

2022

Targeting the HDAC6-Cilium Axis Ameliorates the Pathological Changes Associated with Retinopathy of Prematurity.

Applications

Unspecified application

Species

Unspecified reactive species

Jie Ran,Yao Zhang,Sai Zhang,Haixia Li,Liang Zhang,Qingchao Li,Juan Qin,Dengwen Li,Lei Sun,Songbo Xie,Xiaomin Zhang,Lin Liu,Min Liu,Jun Zhou

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Cytochalasin D, actin polymerization inhibitor

Chemical Structure - Cytochalasin D, actin polymerization inhibitor (AB143484)

Key facts

CAS number

Purity

Form

Source

Molecular weight

Molecular formula

PubChem

Nature

Biochemical name

Canonical smiles

Isomeric smiles

InChi

InChiKey

IUPAC Name

Properties and storage information

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Publications (24)

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