MW 318.4 Da, Purity >98%. Chemiluminescent luciferase substrate. Water soluble derivative of D-Luciferin (ab143654) and analog of D-Luciferin sodium salt (ab145164). Emits light on oxidative decarboxylation in the presence of ATP providing a bioluminescent signal for cellular ATP levels in vivo..
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- Haematologica 109:1755-17652024Histone deacetylase inhibition sensitizes p53-deficient B-cell precursor acute lymphoblastic leukemia to chemotherapy.Applications:Unspecified applicationReactive species:Unspecified reactive speciesWillem P J Cox,Nils Evander,Dorette S Van Ingen Schenau,Gawin R Stoll,Nadia Anderson,Lieke De Groot,Kari J T Grünewald,Rico Hagelaar,Miriam Butler,Roland P Kuiper,Laurens T Van der Meer,Frank N Van LeeuwenPubMed 38124624
- EMBO molecular medicine 15:e164912023Infancy-onset diabetes caused by de-regulated AMPylation of the human endoplasmic reticulum chaperone BiP.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLuke A Perera,Andrew T Hattersley,Heather P Harding,Matthew N Wakeling,Sarah E Flanagan,Ibrahim Mohsina,Jamal Raza,Alice Gardham,David Ron,Elisa De FrancoPubMed 36704923
- Nature 614:136-1432022Dendritic cells direct circadian anti-tumour immune responses.Applications:Unspecified applicationReactive species:Unspecified reactive speciesChen Wang,Coline Barnoud,Mara Cenerenti,Mengzhu Sun,Irene Caffa,Burak Kizil,Ruben Bill,Yuanlong Liu,Robert Pick,Laure Garnier,Olga A Gkountidi,Louise M Ince,Stephan Holtkamp,Nadine Fournier,Olivier Michielin,Daniel E Speiser,Stéphanie Hugues,Alessio Nencioni,Mikaël J Pittet,Camilla Jandus,Christoph ScheiermannPubMed 36470303
- Molecular therapy oncolytics 24:230-2482022Superior infectivity of the fiber chimeric oncolytic adenoviruses Ad5/35 and Ad5/3 over Ad5-delta-24-RGD in primary glioma cultures.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAleksei A Stepanenko,Anastasiia O Sosnovtseva,Marat P Valikhov,Anastasia A Chernysheva,Sergey A Cherepanov,Gaukhar M Yusubalieva,Zsolt Ruzsics,Anastasiia V Lipatova,Vladimir P ChekhoninPubMed 35071746
- Frontiers in cell and developmental biology 9:6211472021STYK1/NOK Promotes Metastasis and Epithelial-Mesenchymal Transition in Non-small Cell Lung Cancer by Suppressing FoxO1 Signaling.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYuanyang Lai,Fang Lin,Xuejiao Wang,Jiao Zhang,Jinghua Xia,Ying Sun,Miaomiao Wen,Xiaofei Li,Zhipei Zhang,Jinbo ZhaoPubMed 34295886
- Scientific reports 11:96832021Thawed cryopreserved synovial mesenchymal stem cells show comparable effects to cultured cells in the inhibition of osteoarthritis progression in rats.Applications:Unspecified applicationReactive species:Unspecified reactive speciesKiyotaka Horiuchi,Nobutake Ozeki,Kentaro Endo,Mitsuru Mizuno,Hisako Katano,Masako Akiyama,Kunikazu Tsuji,Hideyuki Koga,Ichiro SekiyaPubMed 33958682
- Journal of experimental & clinical cancer research : CR 40:652021ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMengzhao Zhang,Lu Wang,Yangyang Yue,Lu Zhang,Tianjie Liu,Minxuan Jing,Xiao Liang,Minghai Ma,Shan Xu,Ke Wang,Xinyang Wang,Jinhai FanPubMed 33573671
Key facts
- CAS number
- 115144-35-9
- Purity
- >= 95%
- Form
- Solid
- Molecular weight
- 318.4 Da
- Molecular formula
- C11H7KN2O3S2
- PubChem identifier
- 135478035
- Nature
- Synthetic
Recommended products
MW 318.4 Da, Purity >98%. Chemiluminescent luciferase substrate. Water soluble derivative of D-Luciferin (ab143654) and analog of D-Luciferin sodium salt (ab145164). Emits light on oxidative decarboxylation in the presence of ATP providing a bioluminescent signal for cellular ATP levels in vivo..
Key facts
- CAS number
- 115144-35-9
- Purity
- >= 95%
- Form
- Solid
- Molecular weight
- 318.4 Da
- Molecular formula
- C11H7KN2O3S2
- PubChem identifier
- 135478035
- Nature
- Synthetic
- Biochemical name
- Potassium (S)-2-(6-hydroxybenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylate
- Biological description
Chemiluminescent luciferase substrate. Water soluble derivative of D-Luciferin (ab143654) and analog of D-Luciferin sodium salt (ab145164). Emits light on oxidative decarboxylation in the presence of ATP providing a bioluminescent signal for cellular ATP levels in vivo.
- Canonical SMILES
- C1C(N=C(S1)C2=NC3=C(S2)C=C(C=C3)O)C(=O)[O-].[K+]
- Isomeric SMILES
- C1[C@@H](N=C(S1)C2=NC3=C(S2)C=C(C=C3)O)C(=O)[O-].[K+]
- InChI
- InChI=1S/C11H8N2O3S2.K/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16;/h1-3,7,14H,4H2,(H,15,16);/q;+1/p-1/t7-;/m1./s1
- InChIKey
- UMBKGTQQGYPQBE-OGFXRTJISA-M
- IUPAC name
- potassium;(4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylate
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions
Notes
This product is manufactured by BioVision, an Abcam company and was previously called 7903 Luciferin, Potassium Salt. 7903-100 is the same size as the 100 mg size of ab143655.
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1 product image
Chemical Structure - D-Luciferin potassium salt, chemiluminescent luciferase substrate (ab143655)
2D chemical structure image of ab143655, D-Luciferin potassium salt, chemiluminescent luciferase substrate
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