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AB143655

D-Luciferin potassium salt, chemiluminescent luciferase substrate

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(13 Publications)

D-Luciferin potassium salt (CAS: 115144-35-9) (ab143655) is a chemiluminescent luciferase substrate is the water soluble derivative of D-Luciferin (ab143654) and analog of D-Luciferin sodium salt (ab145164). Molecular weight is 318.4 g/mol.

- Available in different formats to fit your experimental needs. Larger volume format available upon request
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Chemical Structure - D-Luciferin potassium salt, chemiluminescent luciferase substrate (AB143655)
  • Chemical Structure

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Chemical Structure - D-Luciferin potassium salt, chemiluminescent luciferase substrate (AB143655)

2D chemical structure image of ab143655, D-Luciferin potassium salt, chemiluminescent luciferase substrate

Key facts

CAS number

115144-35-9

Purity

>98%

Form

Solid

form

Molecular weight

318.4 Da

Molecular formula

C<sub>1</sub><sub>1</sub>H<sub>7</sub>KN<sub>2</sub>O<sub>3</sub>S<sub>2</sub>

PubChem

135478035

Nature

Synthetic

Biochemical name

Potassium (S)-2-(6-hydroxybenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylate

Biological description

Chemiluminescent luciferase substrate. Water soluble derivative of D-Luciferin (ab143654) and analog of D-Luciferin sodium salt (ab145164). Emits light on oxidative decarboxylation in the presence of ATP providing a bioluminescent signal for cellular ATP levels in vivo.

Canonical smiles

C1C(N=C(S1)C2=NC3=C(S2)C=C(C=C3)O)C(=O)[O-].[K+]

Isomeric smiles

C1[C@@H](N=C(S1)C2=NC3=C(S2)C=C(C=C3)O)C(=O)[O-].[K+]

InChi

InChI=1S/C11H8N2O3S2.K/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16;/h1-3,7,14H,4H2,(H,15,16);/q;+1/p-1/t7-;/m1./s1

InChiKey

UMBKGTQQGYPQBE-OGFXRTJISA-M

IUPAC Name

potassium;(4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylate

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Product details

The D-Luciferin potassium salt, chemiluminescent luciferase substrate (ab143655)  can be used in reporter gene assays and immunoassays.
ab143655 can be used for bioluminescence imaging assays of the luciferase (LUC) gene linked to a promoter of interest.

This product is manufactured by BioVision, an Abcam company and was previously called 7903 Luciferin, Potassium Salt. 7903-100 is the same size as the 100 mg size of ab143655.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
It is important to note that this product is reported to be light sensitive|Store in the dark|Store under desiccating conditions
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Product protocols

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Publications (13)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 16:4065 PubMed40307219

2025

Gibberellin signaling regulates pectin biosynthesis in Arabidopsis.

Applications

Unspecified application

Species

Unspecified reactive species

Yan Xu,Jinge Du,Ruili Hao,Siqi Ma,Yujiao Ma,Gongke Zhou,Ruibo Hu,Shengjun Li

Nature communications 16:33 PubMed39747871

2025

Wearable electrodriven switch actively delivers macromolecular drugs to fundus in non-invasive and controllable manners.

Applications

Unspecified application

Species

Unspecified reactive species

Xuan Qin,Haoliang Shi,Hongyang Li,Binbin Chu,Jiawei Zhang,Zhen Wen,Xuhui Sun,Houyu Wang,Yao He

EMBO molecular medicine 16:2749-2774 PubMed39433871

2024

Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasis.

Applications

Unspecified application

Species

Unspecified reactive species

Tobias Ackermann,Engy Shokry,Ruhi Deshmukh,Jayanthi Anand,Laura C A Galbraith,Louise Mitchell,Giovanny Rodriguez-Blanco,Victor H Villar,Britt Amber Sterken,Colin Nixon,Sara Zanivan,Karen Blyth,David Sumpton,Saverio Tardito

Nature 634:702-711 PubMed39322664

2024

Single-cell CAR T atlas reveals type 2 function in 8-year leukaemia remission.

Applications

Unspecified application

Species

Unspecified reactive species

Zhiliang Bai,Bing Feng,Susan E McClory,Beatriz Coutinho de Oliveira,Caroline Diorio,Céline Gregoire,Bo Tao,Luojia Yang,Ziran Zhao,Lei Peng,Giacomo Sferruzza,Liqun Zhou,Xiaolei Zhou,Jessica Kerr,Alev Baysoy,Graham Su,Mingyu Yang,Pablo G Camara,Sidi Chen,Li Tang,Carl H June,J Joseph Melenhorst,Stephan A Grupp,Rong Fan

Plant, cell & environment 47:5007-5020 PubMed39132878

2024

Tomato NADPH oxidase SlWfi1 interacts with the effector protein RipBJ of Ralstonia solanacearum to mediate host defence.

Applications

Unspecified application

Species

Unspecified reactive species

Guan-Ming Su,Li-Wen Chu,Chih-Cheng Chien,Pei-Shan Liao,Yu-Chuan Chiu,Chi-Hsin Chang,Tai-Hsiang Chu,Chien-Hui Li,Chien-Sheng Wu,Jaw-Fen Wang,Yi-Sheng Cheng,Chuan-Hsin Chang,Chiu-Ping Cheng

Haematologica 109:1755-1765 PubMed38124624

2024

Histone deacetylase inhibition sensitizes p53-deficient B-cell precursor acute lymphoblastic leukemia to chemotherapy.

Applications

Unspecified application

Species

Unspecified reactive species

Willem P J Cox,Nils Evander,Dorette S Van Ingen Schenau,Gawin R Stoll,Nadia Anderson,Lieke De Groot,Kari J T Grünewald,Rico Hagelaar,Miriam Butler,Roland P Kuiper,Laurens T Van der Meer,Frank N Van Leeuwen

Journal of translational medicine 22:171 PubMed38368374

2024

Combined therapy of CAR-IL-15/IL-15Rα-T cells and GLIPR1 knockdown in cancer cells enhanced anti-tumor effect against gastric cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Jianbin Ye,Qiaoyuan Liu,Yunxuan He,Zhenkun Song,Bao Lin,Zhiwei Hu,Juanyuan Hu,Yunshan Ning,Cheguo Cai,Yan Li

EMBO molecular medicine 15:e16491 PubMed36704923

2023

Infancy-onset diabetes caused by de-regulated AMPylation of the human endoplasmic reticulum chaperone BiP.

Applications

Unspecified application

Species

Unspecified reactive species

Luke A Perera,Andrew T Hattersley,Heather P Harding,Matthew N Wakeling,Sarah E Flanagan,Ibrahim Mohsina,Jamal Raza,Alice Gardham,David Ron,Elisa De Franco

Nature 614:136-143 PubMed36470303

2022

Dendritic cells direct circadian anti-tumour immune responses.

Applications

Unspecified application

Species

Unspecified reactive species

Chen Wang,Coline Barnoud,Mara Cenerenti,Mengzhu Sun,Irene Caffa,Burak Kizil,Ruben Bill,Yuanlong Liu,Robert Pick,Laure Garnier,Olga A Gkountidi,Louise M Ince,Stephan Holtkamp,Nadine Fournier,Olivier Michielin,Daniel E Speiser,Stéphanie Hugues,Alessio Nencioni,Mikaël J Pittet,Camilla Jandus,Christoph Scheiermann

Molecular therapy oncolytics 24:230-248 PubMed35071746

2022

Superior infectivity of the fiber chimeric oncolytic adenoviruses Ad5/35 and Ad5/3 over Ad5-delta-24-RGD in primary glioma cultures.

Applications

Unspecified application

Species

Unspecified reactive species

Aleksei A Stepanenko,Anastasiia O Sosnovtseva,Marat P Valikhov,Anastasia A Chernysheva,Sergey A Cherepanov,Gaukhar M Yusubalieva,Zsolt Ruzsics,Anastasiia V Lipatova,Vladimir P Chekhonin
View all publications
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