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AB275405

DABCYL SE

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MW 366.4 Da, Purity >98%. Long wavelength azo quencher - useful as a reagent to label proteins or peptides through their amino-groups. The succinimidyl ester is reactive with terminal amines or lysines of peptides and other nucleophiles.
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Chemical Structure - DABCYL SE (AB275405)
  • Chemical Structure

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Chemical Structure - DABCYL SE (AB275405)

Chemical structure of DABCYL SE, 146998-31-4

Key facts

CAS number

146998-31-4

Purity

>98%

Form

Solid

form

Molecular weight

366.4 Da

Molecular formula

C<sub>1</sub><sub>9</sub>H<sub>1</sub><sub>8</sub>N<sub>4</sub>O<sub>4</sub>

PubChem

4206604

Nature

Synthetic

Solubility

Soluble in DMSO.

Biochemical name

(E)-2,5-Dioxopyrrolidin-1-yl 4-((4-(dimethylamino)phenyl)diazenyl)benzoate

Biological description

Long wavelength azo quencher - useful as a reagent to label proteins or peptides through their amino-groups. The succinimidyl ester is reactive with terminal amines or lysines of peptides and other nucleophiles.

Canonical smiles

CN(C)C1=CC=C(C=C1)N=NC2=CC=C(C=C2)C(=O)ON3C(=O)CCC3=O

InChi

InChI=1S/C19H18N4O4/c1-22(2)16-9-7-15(8-10-16)21-20-14-5-3-13(4-6-14)19(26)27-23-17(24)11-12-18(23)25/h3-10H,11-12H2,1-2H3

InChiKey

IBOVDNBDQHYNJI-UHFFFAOYSA-N

IUPAC Name

(2,5-dioxopyrrolidin-1-yl) 4-[[4-(dimethylamino)phenyl]diazenyl]benzoate

Excitation/Emission

Ex: 52nm, Em: 450nm

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Complementary Products

Primary Antibodies

AB309481

Anti-TET2 antibody [EPR26694-93]

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Primary Antibodies

AB155335

Anti-ROX antibody

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Primary Antibodies

AB191698

Anti-TET1 antibody - C-terminal

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Secondary Antibodies

AB97035

Goat Anti-Mouse IgG H&L (Cy3 ®) preadsorbed

Immunocytochemistry/ Immunofluorescence - Goat Anti-Mouse IgG H&L (Cy3 ®) preadsorbed (AB97035)

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Product details

This reactive version of DABCYL has an NHS (N-hydroxysuccinimidyl) group that allows easy labeling of proteins or peptides for use in substrates or other detection systems. It has absorption wavelengths that overlap well with EDANS, and some other fluorophores, in FRET-type quenched substrates
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Refer to SDS for further information.

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Product protocols

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Product promise

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