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MW 254.24 Da, Purity >99%. Phytoestrogen, and soy isoflavone. Analog of genistein (ab120112). Various biological actions, including a weak estrogenic / antiestrogenic effect by binding to the nuclear estrogen receptor.

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Images

Chemical Structure - Daidzein, Phytoestrogen (AB120391), expandable thumbnail
  • Functional Studies - Daidzein, Phytoestrogen (AB120391), expandable thumbnail

Publications

Key facts

CAS number

486-66-8

Purity

> 99%

Form

Solid

Molecular weight

254.24 Da

Molecular formula

C15H10O4

PubChem identifier

5281708

Nature

Synthetic

Alternative names

Recommended products

MW 254.24 Da, Purity >99%. Phytoestrogen, and soy isoflavone. Analog of genistein (ab120112). Various biological actions, including a weak estrogenic / antiestrogenic effect by binding to the nuclear estrogen receptor.

Key facts

Purity

> 99%

PubChem identifier

5281708

Solubility

Soluble in DMSO to 100 mM.

Biochemical name

Daidzein

Biological description

Phytoestrogen, and soy isoflavone. Analog of genistein (ab120112). Various biological actions, including a weak estrogenic / antiestrogenic effect by binding to the nuclear estrogen receptor.

Canonical SMILES

C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O

InChI

InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H

InChIKey

ZQSIJRDFPHDXIC-UHFFFAOYSA-N

IUPAC name

7-hydroxy-3-(4-hydroxyphenyl)chromen-4-one

Storage

Shipped at conditions

Ambient - Can Ship with Ice

Appropriate short-term storage conditions

-20°C

Appropriate long-term storage conditions

-20°C

Storage information

Store under desiccating conditions, The product can be stored for up to 12 months

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2 product images

  • Chemical Structure - Daidzein, Phytoestrogen (ab120391), expandable thumbnail

    Chemical Structure - Daidzein, Phytoestrogen (ab120391)

    2D chemical structure image of ab120391, Daidzein, Phytoestrogen

  • Functional Studies - Daidzein, Phytoestrogen (ab120391), expandable thumbnail

    Functional Studies - Daidzein, Phytoestrogen (ab120391)

    ab47489 staining Bcl2 MCF7 cells treated with diadzein (ab120391), by ICC/IF. Decrease in Bcl2 expression correlates with increased concentration of diadzein, as described in literature.
    The cells were incubated at 37°C for 6h in media containing different concentrations of ab120391 (diadzein) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab47489 (5 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (Goat Anti-Rabbit IgG H&L (DyLight® 488) preadsorbed ab96899) at 1/250 dilution was used as the secondary antibody.

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