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AB120810

DAPTA, CCR5 antagonist

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(2 Publications)

MW 856.89 g/mol, Purity >95%. Potent, selective CCR5 antagonist. Synthetic peptide. Selective antiviral entry inhibitor for R5 tropic HIV-1 isolates. Able to attenuate neuroinflammation.
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Chemical Structure - DAPTA, CCR5 antagonist (AB120810)
  • Chemical Structure

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Chemical Structure - DAPTA, CCR5 antagonist (AB120810)

2D chemical structure image of ab120810, DAPTA, CCR5 antagonist

Key facts

CAS number

106362-34-9

Purity

>95%

Form

Solid

form

Molecular weight

856.89 g/mol

Nature

Synthetic

Solubility

Soluble in water to 1 mg/ml

Biological description

Potent, selective CCR5 antagonist. Synthetic peptide. Selective antiviral entry inhibitor for R5 tropic HIV-1 isolates. Able to attenuate neuroinflammation.

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in pharmacology 12:551839 PubMed33953665

2021

miR-4456/CCL3/CCR5 Pathway in the Pathogenesis of Tight Junction Impairment in Chronic Obstructive Pulmonary Disease.

Applications

Unspecified application

Species

Unspecified reactive species

Weiwei Yu,Ting Ye,Jie Ding,Yi Huang,Yang Peng,Qin Xia,Zhang Cuntai

Pathobiology : journal of immunopathology, molecul 86:274-284 PubMed31574524

2019

R5 HIV-1 gp120 Activates p38 MAPK to Induce Rat Cardiomyocyte Injury by the CCR5 Coreceptor.

Applications

Unspecified application

Species

Unspecified reactive species

Rui Gao,Qiujuan Fang,Xi Zhang,Qin Xu,Hanhui Ye,Wenyan Guo,Jiao He,Yahong Chen,Ruixing Wang,Zhijuan Wu,Jing Yu
View all publications

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