Dasatinib, Src family tyrosine kinase (SFK)/Bcl-Abl kinase inhibitor

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(5 Publications)

MW 488 Da, Purity >98%. Potent Src family tyrosine kinase (SFK)/Bcl-Abl kinase inhibitor.Inhibits growth of Bcr-Abl–dependent chronic myeloid leukemia xenografts in nude mice. Anti-tumor activity *in vivo*.

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Alpha-PAK, B lymphocyte kinase, B lymphoid tyrosine kinase, B55, BLK nonreceptor tyrosine kinase, BLK_HUMAN, Beta PAK, CAM kinase II delta, CAMK 2, CAMK 2B, CAMK 2d, CAMK2G, CAMKA, CDKN1A, CaM kinase II, CaM kinase II alpha, CaM kinase II beta, CaM kinase II gamma, CaM kinase II subunit alpha, CaMK-II subunit alpha, Calcium / calmodulin dependent protein kinase II delta, Calcium/calmodulin dependent protein kinase II gamma, Calcium/calmodulin-dependent protein kinase II-alpha, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Camk2a, EC 2.7.10.2, EC 2.7.11.1, GCK family kinase MiNK, GSD9C, Gamma-PAK, Germinal center kinase like kinase, Germinal center kinase-related protein kinase, IMD42, KCC2A_HUMAN, KHS, Kinase homologous to SPS1/STE20, MAP4K3, MAPK/ERK kinase kinase kinase 3, MAPK/ERK kinase kinase kinase 5, MAPK/ERK kinase kinase kinase 6, MAPKKKK3, MEK (MAP/ERK) kinase kinase 6, MEK kinase kinase 3, MEK kinase kinase 5, MEK kinase kinase 6, MEKKK 3, MEKKK 5, MEKKK6, MGC 10442, MGC129539, MGC21111, MINK, MODY 11, MRX30, MRX47, Misshapen NIKs Related kinase, Misshapen like kinase 1, Misshapen/NIK related kinase, Mitogen activated protein kinase kinase kinase kinase 6, NR1F3, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, OPHN3, Oligophrenin 3, P21 (CDKN1A) activated kinase 2, P21 (CDKN1A) activated kinase 3, P21 protein (Cdc42/Rac) activated kinase 1, P21 protein (Cdc42/Rac) activated kinase 3, P21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related), P58, PAK alpha, PAK3beta, PAK65, PAKgamma, PHK gamma LT, PHK gamma T, PSK C3, Phosphorylase b kinase gamma catalytic chain testis/liver isoform, Phosphorylase b kinase gamma catalytic chain, liver/testis isoform, Phosphorylase kinase catalytic subunit gamma 2, Phosphorylase kinase gamma subunit 2, Phosphorylase kinase subunit gamma 2, Phosphorylase kinase, gamma 2 (testis), Phosphorylase kinase, gamma 2 (testis/liver), RAB8IPL1, RAR related orphan nuclear receptor variant 2, RAR related orphan receptor C, isoform a, RAR related orphan receptor gamma, RAR-related orphan receptor C, RORG_HUMAN, RP23-122P1.6, RZR GAMMA, RZRG, Retinoic acid binding receptor gamma, Retinoid-related orphan receptor-gamma, Rorc, S6/H4 kinase, STE20 homolog, yeast, Serine/threonine protein kinase PAK 2, Serine/threonine protein kinase PAK 3, Serine/threonine protein kinase PHKG2, Serine/threonine-protein kinase PAK 1, TOR, TUBA1, TUBA1A, TUBA2, TUBA3, TUBA3C, TUBA4A, Tubulin, alpha 1a, Tubulin, alpha 3c, Tubulin, alpha 4a, Tyrosine kinase B lymphocyte specific, Tyrosine protein kinase, Tyrosine-protein kinase BLK, Ysk2, ZC3, bPAK, calcium/calmodulin-dependent protein kinase II beta, hMINK, hPAK3, mitogen-activated protein kinase kinase kinase kinase 3, p21 activated kinase 3, p21 protein (Cdc42/Rac)-activated kinase 2, p21-activated kinase 1, p21-activated kinase 2, p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast), p55-BLK, p65-PAK