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AB120016

Desmethyl YM298198 hydrochloride, Analogue of mGlu1 antagonist YM298198

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(1 Publication)

MW 364.9 Da, Purity >99%. Derivative of mGlu1 antagonist YM298198 (ab120015). Achieve your results faster with highly validated, pure and trusted compounds.

View Alternative Names

1,8-cineole 2-exo-monooxygenase, Albendazole monooxygenase, Albendazole sulfoxidase, CP33, CP34, CP3A4_HUMAN, CYP3, CYP3A, CYP3A3, CYP3A4, CYPIIIA3, CYPIIIA4, Cytochrome P450 3A3, Cytochrome P450 3A4, Cytochrome P450 HLp, Cytochrome P450 NF-25, Cytochrome P450 family 3 subfamily A polypeptide 4, Cytochrome P450 subfamily IIIA polypeptide 4, Cytochrome P450-PCN1, GLUR, Glucocorticoid inducible P450, HLP, MGC126680, NF 25, Nifedipine oxidase, P450 III steroid inducible, P450 PCN1, P450, family III, P450C3, Quinine 3-monooxygenase, Smp_128940, Taurochenodeoxycholate 6-alpha-hydroxylase, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4

1 Images
Chemical Structure - Desmethyl YM298198 hydrochloride, Analogue of mGlu1 antagonist YM298198 (AB120016)
  • Chemical Structure

Lab

Chemical Structure - Desmethyl YM298198 hydrochloride, Analogue of mGlu1 antagonist YM298198 (AB120016)

2D chemical structure image of ab120016, Desmethyl YM298198 hydrochloride, Analogue of mGlu1 antagonist YM298198

Key facts

CAS number

1177767-57-5

Purity

>99%

Form

Solid

form

Molecular weight

364.9 Da

Molecular formula

C<sub>1</sub><sub>7</sub>H<sub>2</sub><sub>1</sub>ClN<sub>4</sub>OS

PubChem

16759180

Nature

Synthetic

Solubility

Soluble in DMSO to 50 mM

Biochemical name

6-Amino-N-cyclohexyl-3-methylthiazolo[3,2-A]benzimidazole-2-carboxamide hydrochloride

Biological description

Derivative of mGlu1 antagonist YM298198 (ab120015).

Canonical smiles

CC1=C(SC2=NC3=C(N12)C=C(C=C3)N)C(=O)NC4CCCCC4.Cl

InChi

InChI=1S/C17H20N4OS.ClH/c1-10-15(16(22)19-12-5-3-2-4-6-12)23-17-20-13-8-7-11(18)9-14(13)21(10)17;/h7-9,12H,2-6,18H2,1H3,(H,19,22);1H

InChiKey

SWKZWXJQIDXGLX-UHFFFAOYSA-N

IUPAC Name

7-amino-N-cyclohexyl-1-methyl-[1,3]thiazolo[3,2-a]benzimidazole-2-carboxamide;hydrochloride

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Complementary Products

Primary Antibodies

AB75814

Anti-GSK3 beta (phospho S9) antibody [EPR2286Y]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GSK3 beta (phospho S9) antibody [EPR2286Y] (AB75814)

  • 4
  • 10
Primary Antibodies

AB137550

Anti-Nrf2 antibody

KO Validated

Western blot - Anti-Nrf2 antibody (AB137550)

  • 4
  • 7
Primary Antibodies

AB93926

Anti-GSK3 beta antibody [3D10]

Western blot - Anti-GSK3 beta antibody [3D10] (AB93926)

  • 4
  • 8
Primary Antibodies

AB112501

Anti-JNK1 + JNK2 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-JNK1 + JNK2 antibody (AB112501)

  • 0
  • 0
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature neuroscience 13:1216-24 PubMed20852624

2010

Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95.

Applications

Unspecified application

Species

Unspecified reactive species

Jihoon Jo,Gi Hoon Son,Bryony L Winters,Myung Jong Kim,Daniel J Whitcomb,Bryony A Dickinson,Youn-Bok Lee,Kensuke Futai,Mascia Amici,Morgan Sheng,Graham L Collingridge,Kwangwook Cho
View all publications
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Product promise

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