AB145360

Dihydroethidium (DHE), Blue fluorescent dye

Name: Dihydroethidium (DHE), Blue fluorescent dye (CAS 104821-25-2) | Abcam
Brand: Abcam Limited
SKU: AB145360

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(9 Publications)

MW 315.4 Da. Cell-permeable blue fluorescent dye. Redox indicator. Loses fluorescence on oxidation to ethidium (ab141391). Detects superoxide radical in vivo. .

1 Images

Chemical Structure - Dihydroethidium (DHE), Blue fluorescent dye (AB145360)

Chemical Structure

Lab

Chemical Structure - Dihydroethidium (DHE), Blue fluorescent dye (AB145360)

2D chemical structure image of ab145360, Dihydroethidium (DHE), Blue fluorescent dye

Key facts

CAS number

104821-25-2

Form

Solid

form

Molecular weight

315.4 Da

Molecular formula

C21H21N3

PubChem

128682

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Biochemical name

Dihydroethidium

Biological description

Cell-permeable blue fluorescent dye. Redox indicator. Loses fluorescence on oxidation to ethidium (ab141391). Detects superoxide radical in vivo.

Canonical smiles

CCN1C(C2=C(C=CC(=C2)N)C3=C1C=C(C=C3)N)C4=CC=CC=C4

InChi

InChI=1S/C21H21N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,21H,2,22-23H2,1H3

InChiKey

XYJODUBPWNZLML-UHFFFAOYSA-N

IUPAC Name

5-ethyl-6-phenyl-6H-phenanthridine-3,8-diamine

Excitation/Emission

Ex: 392nm, Em: 410nm

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Properties and storage information

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

-20°C

Appropriate long-term storage conditions

-20°C

Storage information

Store under desiccating conditions|The product can be stored for up to 12 months

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Product protocols

Visit the General protocols
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Publications (9)

Recent publications for all applications. Explore the full list and refine your search

NPJ Parkinson's disease 10:233 PubMed39663354

2024

Mitochondrial oxidant stress promotes α-synuclein aggregation and spreading in mice with mutated glucocerebrosidase.

Applications

Unspecified application

Species

Unspecified reactive species

Pietro La Vitola,Eva M Szegö,Rita Pinto-Costa,Angela Rollar,Eugenia Harbachova,Anthony Hv Schapira,Ayse Ulusoy,Donato A Di Monte

International journal of molecular medicine 54: PubMed38994762

2024

Triptonide protects retinal cells from oxidative damage via activation of Nrf2 signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Jinjing Li,Jiajun Li,Yuan Cao,Jin Yuan,Yaming Shen,Linyi Lei,Keran Li

Communications biology 6:13 PubMed36609486

2023

Highly concentrated trehalose induces prohealing senescence-like state in fibroblasts via CDKN1A/p21.

Applications

Unspecified application

Species

Unspecified reactive species

Jun Muto,Shinji Fukuda,Kenji Watanabe,Xiuju Dai,Teruko Tsuda,Takeshi Kiyoi,Kenji Kameda,Ryosuke Kawakami,Hideki Mori,Ken Shiraishi,Masamoto Murakami,Takeshi Imamura,Shigeki Higashiyama,Yasuhiro Fujisawa,Yoichi Mizukami,Koji Sayama

Frontiers in pharmacology 13:1037151 PubMed36483733

2022

Ciprofol attenuates the isoproterenol-induced oxidative damage, inflammatory response and cardiomyocyte apoptosis.

Applications

Unspecified application

Species

Unspecified reactive species

Yunzhao Yang,Zhongyuan Xia,Cheng Xu,Chunchun Zhai,Xi Yu,Siqi Li

International journal of molecular sciences 23: PubMed36142834

2022

Dual Mode of Mitochondrial ROS Action during Reprogramming to Pluripotency.

Applications

Unspecified application

Species

Unspecified reactive species

Elena V Skvortsova,Igor B Nazarov,Alexey N Tomilin,Sergey A Sinenko

iScience 25:104577 PubMed35789849

2022

Microgravity-induced stress mechanisms in human stem cell-derived cardiomyocytes.

Applications

Unspecified application

Species

Unspecified reactive species

Aviseka Acharya,Harshal Nemade,Symeon Papadopoulos,Jürgen Hescheler,Felix Neumaier,Toni Schneider,Krishna Rajendra Prasad,Khadija Khan,Ruth Hemmersbach,Eduardo Gade Gusmao,Athanasia Mizi,Argyris Papantonis,Agapios Sachinidis

Physiologia plantarum 173:2334-2349 PubMed34625959

2021

A rice R2R3-MYB (OsC1) transcriptional regulator improves oxidative stress tolerance by modulating anthocyanin biosynthesis.

Applications

Unspecified application

Species

Unspecified reactive species

Gouranga Upadhyaya,Arup Das,Sudipta Ray

Neurotoxicity research 38:785-792 PubMed32651843

2020

Phoenixin-20 Ameliorates Lipopolysaccharide-Induced Activation of Microglial NLRP3 Inflammasome.

Applications

Unspecified application

Species

Unspecified reactive species

Xiangliang Zeng,Yanchun Li,Sicong Ma,Yidan Tang,Hanwen Li

Frontiers in plant science 9:136 PubMed29491874

2018

Dehydrins Impart Protection against Oxidative Stress in Transgenic Tobacco Plants.

Applications

Unspecified application

Species

Unspecified reactive species

Tanmoy Halder,Gouranga Upadhyaya,Chandra Basak,Arup Das,Chandrima Chakraborty,Sudipta Ray

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Dihydroethidium (DHE), Blue fluorescent dye

Chemical Structure - Dihydroethidium (DHE), Blue fluorescent dye (AB145360)

Key facts

CAS number

Form

Molecular weight

Molecular formula

PubChem

Nature

Solubility

Biochemical name

Biological description

Canonical smiles

InChi

InChiKey

IUPAC Name

Excitation/Emission

Properties and storage information

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Publications (9)

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