Skip to main content

MW 346.4 Da, Purity >98%. Cell-permeable fluorescent probe for ROS. Redox sensor. Detects presence of peroxynitrite. Fluoresces brighter extracellularly than Dihydrofluorescein diacetate (ab145351) but less bight intracellularly.

Be the first to review this product! Submit a review

Images

Chemical Structure - Dihydrorhodamine 123, Fluorescent probe for ROS (AB145260), expandable thumbnail

Key facts

CAS number
109244-58-8
Purity
> 98%
Form
Solid
Molecular weight
346.4 Da
Molecular formula
C21H18N2O3
PubChem identifier
105032
Nature
Synthetic
Excitation/Emission
Ex: 500nm, Em: 536nm

Target data

Recommended products

MW 346.4 Da, Purity >98%. Cell-permeable fluorescent probe for ROS. Redox sensor. Detects presence of peroxynitrite. Fluoresces brighter extracellularly than Dihydrofluorescein diacetate (ab145351) but less bight intracellularly.

Key facts

Purity
> 98%
PubChem identifier
105032
Solubility

Soluble in ethanol to 25 mM.

Soluble in DMSO to 25 mM.

Biochemical name
Dihydrorhodamine 123
Biological description

Cell-permeable fluorescent probe for ROS. Redox sensor. Detects presence of peroxynitrite. Fluoresces brighter extracellularly than Dihydrofluorescein diacetate (ab145351) but less bight intracellularly.

Canonical SMILES
COC(=O)C1=CC=CC=C1C2C3=C(C=C(C=C3)N)OC4=C2C=CC(=C4)N
InChI
InChI=1S/C21H18N2O3/c1-25-21(24)15-5-3-2-4-14(15)20-16-8-6-12(22)10-18(16)26-19-11-13(23)7-9-17(19)20/h2-11,20H,22-23H2,1H3
InChIKey
FNEZBBILNYNQGC-UHFFFAOYSA-N
IUPAC name
methyl 2-(3,6-diamino-9H-xanthen-9-yl)benzoate
Excitation/Emission
Ex: 500nm, Em: 536nm

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • Chemical Structure - Dihydrorhodamine 123, Fluorescent probe for ROS (ab145260), expandable thumbnail

    Chemical Structure - Dihydrorhodamine 123, Fluorescent probe for ROS (ab145260)

    Chemical structure of ab145260, Dihydrorhodamine 123, Fluorescent probe for ROS

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com