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MW 256.34 Da, Purity >99%. HIF-1α inhibitor that promotes degradation of HIF-1α protein by dissociating Hsp90 from HIF-1α. Inhibits steroidogenesis and down regulates rate-limiting enzymes (StAR) in the estradiol biosynthesis pathway.

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Images

Chemical Structure - Dimethyl-bisphenol A, HIF-1alpha inhibitor (AB141642), expandable thumbnail

Key facts

CAS number
1568-83-8
Purity
> 99%
Form
Solid
Molecular weight
256.34 Da
Molecular formula
C17H20O2
PubChem identifier
617780
Nature
Synthetic

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MW 256.34 Da, Purity >99%. HIF-1α inhibitor that promotes degradation of HIF-1α protein by dissociating Hsp90 from HIF-1α. Inhibits steroidogenesis and down regulates rate-limiting enzymes (StAR) in the estradiol biosynthesis pathway.

Key facts

Purity
> 99%
PubChem identifier
617780
Solubility

Soluble in ethanol to 75 mM.

Soluble in DMSO to 100 mM.

Biochemical name
Benzene, 1,1'-(1-methylethylidene)bis[4-methoxy-
Biological description

HIF-1α inhibitor that promotes degradation of HIF-1α protein by dissociating Hsp90 from HIF-1α. Inhibits steroidogenesis and down regulates rate-limiting enzymes (StAR) in the estradiol biosynthesis pathway.

Canonical SMILES
CC(C)(C1=CC=C(C=C1)OC)C2=CC=C(C=C2)OC
InChI
InChI=1S/C17H20O2/c1-17(2,13-5-9-15(18-3)10-6-13)14-7-11-16(19-4)12-8-14/h5-12H,1-4H3
InChIKey
OJYIBEYSBXIQOP-UHFFFAOYSA-N
IUPAC name
1-methoxy-4-[2-(4-methoxyphenyl)propan-2-yl]benzene

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

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1 product image

  • Chemical Structure - Dimethyl-bisphenol A, HIF-1alpha inhibitor (ab141642), expandable thumbnail

    Chemical Structure - Dimethyl-bisphenol A, HIF-1alpha inhibitor (ab141642)

    2D chemical structure image of ab141642, Dimethyl-bisphenol A, HIF-1alpha inhibitor

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Product protocols

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