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AB141642

Dimethyl-bisphenol A, HIF-1alpha inhibitor

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MW 256.34 Da, Purity >99%. HIF-1α inhibitor that promotes degradation of HIF-1α protein by dissociating Hsp90 from HIF-1α. Inhibits steroidogenesis and down regulates rate-limiting enzymes (StAR) in the estradiol biosynthesis pathway.
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Chemical Structure - Dimethyl-bisphenol A, HIF-1alpha inhibitor (AB141642)
  • Chemical Structure

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Chemical Structure - Dimethyl-bisphenol A, HIF-1alpha inhibitor (AB141642)

2D chemical structure image of ab141642, Dimethyl-bisphenol A, HIF-1alpha inhibitor

Key facts

CAS number

1568-83-8

Purity

>99%

Form

Solid

form

Molecular weight

256.34 Da

Molecular formula

C<sub>1</sub><sub>7</sub>H<sub>2</sub><sub>0</sub>O<sub>2</sub>

PubChem

617780

Nature

Synthetic

Solubility

Soluble in ethanol to 75 mM

Soluble in DMSO to 100 mM

Biochemical name

Benzene, 1,1'-(1-methylethylidene)bis[4-methoxy-

Biological description

HIF-1α inhibitor that promotes degradation of HIF-1α protein by dissociating Hsp90 from HIF-1α. Inhibits steroidogenesis and down regulates rate-limiting enzymes (StAR) in the estradiol biosynthesis pathway.

Canonical smiles

CC(C)(C1=CC=C(C=C1)OC)C2=CC=C(C=C2)OC

InChi

InChI=1S/C17H20O2/c1-17(2,13-5-9-15(18-3)10-6-13)14-7-11-16(19-4)12-8-14/h5-12H,1-4H3

InChiKey

OJYIBEYSBXIQOP-UHFFFAOYSA-N

IUPAC Name

1-methoxy-4-[2-(4-methoxyphenyl)propan-2-yl]benzene

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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